Results 11 to 20 of about 6,571 (196)

Transcriptional and post-transcriptional control of autophagy and adipogenesis by YBX1

Cell Death and Disease, 2023
Obesity is strongly associated with metabolic diseases, which have become a global health problem. Exploring the underlying mechanism of adipogenesis is crucial for the treatment of excess white fat.
Ruifan Wu, Shengchun Feng, Fan Li, Gang Shu, Lina Wang, Ping Gao, Xiaotong Zhu, Canjun Zhu, Songbo Wang, Qingyan Jiang   +9 more
doaj   +4 more sources

YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis [PDF]

PLoS ONE, 2013
MIA/CD-RAP is a small, secreted protein involved in cartilage differentiation and melanoma progression. We recently revealed that p54(nrb) acts as a mediator of MIA/CD-RAP action to promote chondrogenesis and the progression of malignant melanoma. As the
Bosserhoff, Anja-Katrin, Katharina Meyer, Rainer Spang, Birgit Schittek, Schmid Rainer, Schmid, Rainer, Meyer Katharina, Spang, Rainer, Anja Katrin Bosserhoff, Bosserhoff Anja Katrin, Rainer Schmid, Schittek Birgit, Schittek, Birgit, Meyer, Katharina, Spang Rainer   +14 more
core   +7 more sources

YBX1 (Y box binding protein 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on YBX1 (Y box binding protein 1), with data on DNA, on the protein encoded, and where the gene is ...
Sorokin, A, Evdokimova, V
core   +4 more sources

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms [PDF]

Nature, 2020
Janus kinases (JAKs) mediate responses to cytokines, hormones and growth factors in haematopoietic cells1,2. The JAK gene JAK2 is frequently mutated in the ageing haematopoietic system3,4 and in haematopoietic cancers5.
Francesca Palandri, Rahmig, S., Mohr, J., Iain Coldham, Carolin Herzog, Bullinger, L., Mullally, A., Ungelenk, M., Meiler, A., Jayavelu, A., Claudia Waskow, Hübner, C.A., Heidel, F.H., Austin, R., Isermann, B., Coldham, I., Philipp J. Jost, Jost, P.J., Steven W. Lane, Berend Isermann, Mann, M., Huber, N., Bärbel Edelmann-Stephan, Jayavelu, A.K., Frank Edlich, Martin Ungelenk, Herzog, C., Schröder, N., Hübner, C., Waskow, C., Florian Perner, Mertens, P., Hochhaus, A., Perner, F., Robert Zeiser, Jost, P., Lars Bullinger, Edlich, F., Schnöder, T.M., Juliane Mohr, Schnöder, T., Lane, S., Mertens, P.R., Amit U. Sinha, Jilg, S., Gurumoorthy Krishnamoorthy, Florian H. Heidel, Brandt, S., Lane, S.W., Susann Rahmig, Palandri, F., Ann Mullally, Ashok Kumar Jayavelu, Matthias Mann, Ernst, T., Heidel, F., Arno Meiler, Edelmann-Stephan, B., Sinha, A., Nicolas Huber, Rebecca Austin, Thomas Ernst, Sinha, A.U., Sabine Brandt, Christian A. Hübner, Tina M. Schnöder, Peter R. Mertens, Nicolas Schröder, Stefanie Jilg, Zeiser, R., Krishnamoorthy, G., Andreas Hochhaus, Edlich, Frank, Mann, Matthias, Heidel, Florian H., Zeiser, Robert, Schnöder, Tina M., Jayavelu, Ashok Kumar   +77 more
core   +9 more sources

Expression of YBX1 and FOXA1 in Gastric Cancer and Their Clinicopathological Significance

Zhongliu Fangzhi Yanjiu, 2022
Objective To explore the expression levels of YBX1 and FOXA1 in gastric cancer tissues and determine their relationship with prognosis. Methods A total of 131 patients with gastric cancer were studied, and the corresponding adjacent normal tissues of ...
PEI Zhenghao, ZHANG Hu, WANG Jun, HAO Yang   +3 more
doaj   +2 more sources

PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer

Cell Death Discovery
Breast cancer is the second leading cause of death in women worldwide, with triple-negative breast cancer (TNBC) having the worst prognosis. Although there are numerous studies on TNBC, there is no effective treatment for it, and it is still a major ...
Linyu Wu, Shanshan Huang, Wenwen Tian, Peng Liu, Yi Xie, Yu Qiu, Xing Li, Yuhui Tang, Shaoquan Zheng, Yuying Sun, Hailin Tang, Wei Du, Weige Tan, Xinhua Xie   +13 more
doaj   +3 more sources

The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis [PDF]

Journal of Experimental & Clinical Cancer Research, 2019
Background Renal cell carcinoma (RCC) is a deadly urological tumor that remains largely incurable. Our limited understanding of key molecular mechanisms underlying RCC invasion and metastasis has hampered efforts to identify molecular drivers with ...
Yong Wang, Jing Su, Yiting Wang, Donghe Fu, Justin E. Ideozu, Hua Geng, Qiqi Cui, Chao Wang, Ruibing Chen, Yixi Yu, Yuanjie Niu, Dan Yue   +11 more
doaj   +3 more sources

Uncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer [PDF]

Oncogenesis, 2016
The transcription factor YBX1 can act as a mediator of signals transmitted via the EGFR–RAS–MAPK axis. YBX1 expression has been associated with tumor progression and prognosis in multiple types of cancer.
Rivera, M., Bläker, H., Royer, H.-D., Schäfer, R., Morkel, M., Gieseler, C., Sers, C., Dietel, M., Roßner, F.   +8 more
core   +4 more sources

YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma [PDF]

Frontiers in Oncology, 2021
Abnormal expression of the transcription factor Y-box-binding protein-1 (YBX1) is associated with the proliferation, migration, aggressiveness, and stem-like properties of various cancers.
Qiang Xie, Qiang Xie, Shilei Zhao, Shilei Zhao, Wenzhi Liu, Wenzhi Liu, Yanwei Cui, Fengzhou Li, Fengzhou Li, Zhuoshi Li, Zhuoshi Li, Tao Guo, Tao Guo, Wendan Yu, Wei Guo, Wuguo Deng, Chundong Gu, Chundong Gu   +17 more
doaj   +3 more sources

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level [PDF]

Nature Communications, 2018
The integrity of stratified epithelia depends on the ability of progenitor cells to maintain a balance between proliferation and differentiation.
Gian Luca Negri, Kevin K. Lee, Horos, Rastislav, Lee, Kevin K., Poul H. Sorensen, Wang, Jun, Sorensen, Poul H., Hentze, Matthias W., Matthias W. Hentze, Kwon, Eunjeong, Jun Wang, Eunjeong Kwon, Sam W. Lee, Anna Mandinova, Lee, Sam, Rastislav Horos, Neel, Victor, Negri, Gian Luca, Kristina Todorova, Victor A. Neel, Todorova, Kristina, Mandinova, Anna   +21 more
core   +6 more sources