Results 11 to 20 of about 5,418 (159)
Transcriptional and post-transcriptional control of autophagy and adipogenesis by YBX1
Cell Death and Disease, 2023 Obesity is strongly associated with metabolic diseases, which have become a global health problem. Exploring the underlying mechanism of adipogenesis is crucial for the treatment of excess white fat.
Ruifan Wu +9 more
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The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis [PDF]
Journal of Experimental & Clinical Cancer Research, 2019 Background Renal cell carcinoma (RCC) is a deadly urological tumor that remains largely incurable. Our limited understanding of key molecular mechanisms underlying RCC invasion and metastasis has hampered efforts to identify molecular drivers with ...
Yong Wang +11 more
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Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish [PDF]
FEBS Open Bio, 2021 Y‐box‐binding protein 1 (Ybx1, YB‐1), also known as Y‐box transcription factor, is involved in a variety of biological processes (BPs) and pathways, including embryogenesis, reproduction and development in vertebrates.
Chen Huang +4 more
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Cell Death DiscoveryBreast cancer is the second leading cause of death in women worldwide, with triple-negative breast cancer (TNBC) having the worst prognosis. Although there are numerous studies on TNBC, there is no effective treatment for it, and it is still a major ...
Linyu Wu +13 more
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YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development [PDF]
Cell & Bioscience, 2022 Background In mammals, maternal gene products decay and zygotic genome activation (ZGA) during maternal to zygotic transition (MZT) is critical for the early embryogenesis.
Mingtian Deng +6 more
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YBX1: A Multifunctional Protein in Senescence and Immune Regulation
Current Issues in Molecular BiologyThe Y-box binding protein 1 (YBX1) is a multifunctional protein with a wide range of roles in cell biology. It plays a crucial role in immune modulation, senescence, and disease progression.
Wenze Zhang +5 more
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Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates [PDF]
eLife, 2021 Exosomes may mediate cell-to-cell communication by transporting various proteins and nucleic acids to neighboring cells. Some protein and RNA cargoes are significantly enriched in exosomes.
Xiao-Man Liu, Liang Ma, Randy Schekman
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Advanced ScienceThe modification and recognition of 5‐methylcytosine (m5C) are involved in the initiation and progression of various tumor types. However, the precise role and potential mechanism of Y‐box‐binding protein 1 (YBX1) in esophageal squamous cell carcinoma ...
Yu Chen, Guangying Cui, Weiwei Wang
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ybx1 acts upstream of atoh1a to promote the rapid regeneration of hair cells in zebrafish lateral-line neuromasts [PDF]
PeerJLike the sensory organs of the human inner ear, the lateral-line neuromasts (NMs) of fish such as the zebrafish (Danio rerio) contain mechanosensory hair cells (HCs) that are surrounded by supporting cells (SCs).
Caleb C. Reagor +2 more
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YBX1: an RNA/DNA-binding protein that affects disease progression
Frontiers in OncologyYBX1 is a member of the Y-box transcription factor family and is a multifunctional RNA/DNA-binding protein characterized by a highly conserved cold shock domain (CSD).
Xifeng Zheng +8 more
doaj +3 more sources