Results 21 to 30 of about 5,418 (159)
Advanced ScienceSpinal cord injury (SCI) is a severe injury to the central nervous system, and its treatment is always a major medical challenge. Proinflammatory cell death is considered an important factor affecting neuroinflammation and the prognosis after injury ...
Junsong Wu
exaly +2 more sources
Expression of YBX1 and FOXA1 in Gastric Cancer and Their Clinicopathological Significance
Zhongliu Fangzhi Yanjiu, 2022 Objective To explore the expression levels of YBX1 and FOXA1 in gastric cancer tissues and determine their relationship with prognosis. Methods A total of 131 patients with gastric cancer were studied, and the corresponding adjacent normal tissues of ...
PEI Zhenghao +3 more
doaj +1 more source
The Pleiotropic Effects of YBX1 on HTLV-1 Transcription
International Journal of Molecular Sciences, 2023 HTLV-1 is an oncogenic human retrovirus and the etiologic agent of the highly aggressive ATL malignancy. Two viral genes, Tax and Hbz, are individually linked to oncogenic transformation and play an important role in the pathogenic process. Consequently, regulation of HTLV-1 gene expression is a central feature in the viral lifecycle and directly ...
Susan Smith +10 more
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YBX1 (Y box binding protein 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on YBX1 (Y box binding protein 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Evdokimova, V, Sorokin, A
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LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis [PDF]
International Journal of Molecular Sciences, 2020 Oral submucous fibrosis (OSF) has been recognized as a precancerous disorder in the oral cavity. Great effort has been made to inhibit the malignant progression of OSF over the past decades, but the cure of this fibrosis disease has not been discovered. In the present study, we found that a long noncoding RNA, LINC00312, was upregulated in OSF tissues,
Chuan-Hang Yu +6 more
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Isoimperatorin improves osteoporosis by increasing YBX1 expression to promote BGLAP m5C modification
Scientific ReportsOsteoporosis is a chronic metabolic bone disease that is prone to fractures. Isoimperatorin (ISO) has been shown to alleviate the bone loss in ovariectomized (OVX) rats.
Guang Hu +3 more
doaj +3 more sources
Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos
Frontiers in Cell and Developmental Biology, 2023 Y-box binding protein 1 (YBX1) plays important roles in RNA stabilization, translation, transcriptional regulation, and mitophagy. However, its effects on porcine preimplantation embryos remain unclear. In this study, we knocked down YBX1 in the one-cell
Wen-Jie Jiang +7 more
doaj +1 more source
YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia
Blood Advances, 2023 Abstract Y-box-binding protein 1 (YBX1), a member of the RNA-binding protein family, is a critical regulator of cell survival in various solid tumors and acute myeloid leukemia. However, the function of YBX1 in T-cell acute lymphoblastic leukemia (T-ALL) remains elusive.
Huan Li +12 more
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C1QBP Regulates YBX1 to Suppress the Androgen Receptor (AR)-Enhanced RCC Cell Invasion
Neoplasia: An International Journal for Oncology Research, 2017 Early studies suggested that the androgen receptor (AR) might play important roles to promote the renal cell carcinoma (RCC) progression; however, the detailed mechanisms remain unclear.
Dan Yue +4 more
doaj +1 more source
Cell Death and Disease, 2022 NSCLC is common and is the primary cause of cancer-related deaths due to a lack of early diagnosis and its propensity for metastasis. The pathogenesis of NSCLC is still unclear.
HongBo Su +3 more
doaj +1 more source