Results 41 to 50 of about 6,571 (196)
C1QBP Regulates YBX1 to Suppress the Androgen Receptor (AR)-Enhanced RCC Cell Invasion
Neoplasia: An International Journal for Oncology Research, 2017 Early studies suggested that the androgen receptor (AR) might play important roles to promote the renal cell carcinoma (RCC) progression; however, the detailed mechanisms remain unclear.
Dan Yue +4 more
doaj +1 more source
YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC [PDF]
Cell Death & Disease, 2020 AbstractY-box binding protein 1 (YBX1) is involved in the development of multiple types of tumors. However, the relationship between YBX1 and autophagy in non-small cell lung cancer (NSCLC) remains unclear. In this study, we analyzed the expression and clinical significance of YBX1 and markers of autophagy (LC3I/II) in NSCLC and examined their roles in
Cui, Yanwei +15 more
openaire +2 more sources
Circular RNA hsa_circ_0062682 Binds to YBX1 and Promotes Oncogenesis in Hepatocellular Carcinoma
Cancers, 2022 Circular RNAs (circRNAs) have been shown to play an important role in the pathogenesis of hepatocellular carcinoma (HCC). By implementing available transcriptomic analyses of HCC patients, we identified an upregulated circRNA hsa_circ_0062682. Stable perturbations of hsa_circ_0062682 in Huh-7 and SNU-449 cell lines influenced colony formation ...
Rok Razpotnik +4 more
openaire +3 more sources
Cell Death and Disease, 2022 NSCLC is common and is the primary cause of cancer-related deaths due to a lack of early diagnosis and its propensity for metastasis. The pathogenesis of NSCLC is still unclear.
HongBo Su +3 more
doaj +1 more source
YBX1 mediates translation of oncogenic transcripts to control cell competition in AML [PDF]
Leukemia, 2021 AbstractPersistence of malignant clones is a major determinant of adverse outcome in patients with hematologic malignancies. Despite the fact that the majority of patients with acute myeloid leukemia (AML) achieve complete remission after chemotherapy, a large proportion of them relapse as a result of residual malignant cells.
Florian Perner +21 more
openaire +5 more sources
YBX1 promotes angiogenesis after myocardial infarction by stabilizing HIF1α mRNA via m6A signaling
iScienceSummary: Angiogenesis is essential for myocardial repair after myocardial infarction (MI). While Y-box binding protein 1 (YBX1) is well-established in cancer biology, its role in post-MI angiogenesis remains unknown. Here, we show that YBX1 expression is
Fangfang Bi +13 more
doaj +1 more source
YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro [PDF]
, 2017 a Selected genes were used to validate the microarray data analysis using qPCR and the expression of all of the genes showed consistent patterns when compared to the microarray data.
Sukanya Shyamasundar +17 more
core +1 more source
LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis [PDF]
International Journal of Molecular Sciences, 2020 Oral submucous fibrosis (OSF) has been recognized as a precancerous disorder in the oral cavity. Great effort has been made to inhibit the malignant progression of OSF over the past decades, but the cure of this fibrosis disease has not been discovered. In the present study, we found that a long noncoding RNA, LINC00312, was upregulated in OSF tissues,
Chuan-Hang Yu +6 more
openaire +2 more sources
The Journal of Reproduction and DevelopmentSpermatogenesis is a complex process that is required for sperm production. Multiple RNA-binding proteins participate in regulating spermatogenesis.
Yan HAN +6 more
doaj +1 more source
Novel Serine 176 Phosphorylation of YBX1 Activates NF-κB in Colon Cancer
, 2017 Y box protein 1 (YBX1) is a well known oncoprotein that has tumor-promoting functions. YBX1 is widely considered to be an attractive therapeutic target in cancer.
Jiang, Guanglong +8 more
core +1 more source