Results 61 to 70 of about 5,562 (124)

5-methylcytosine regulated CCNL2 promotes tumorigenesis and cisplatin resistance of ovarian cancer with therapeutic implications

Journal of Ovarian Research
Backgroud Ovarian cancer (OC) is the most lethal gynecological tumor, primarily due to resistance to chemotherapy. Cyclin L2 (CCNL2) is a novel member of the cyclin family and mainly localized in nucleus.
Kai Zhang, Guiyun Cheng, Wenwen Jiang, Beihua Kong, Shu Yao, Xihan Liu   +5 more
doaj   +1 more source

TAGLN2 induces resistance signature ISGs by activating AKT-YBX1 signal with dual pathways and mediates the IFN-related DNA damage resistance in gastric cancer

Cell Death and Disease
Recently, various cancer types have been identified to express a distinct subset of Interferon-stimulated genes (ISGs) that mediate therapy resistance.
Huiqin Zhuo, Jingjing Hou, Zhijun Hong, Shuqi Yu, Huifang Peng, Lihua Zhang, Wen Xie, Xuehui Hong   +7 more
doaj   +1 more source

PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes

Cell Communication and Signaling
Timely and accurate translation of maternal mRNA is essential for oocyte maturation and early embryonic development. Previous studies have highlighted the importance of Primordial Germ cell 7 (PGC7) as a maternal factor in maintaining DNA methylation of ...
Yingxiang Liu, Peiwen Feng, Xing Wei, Hongyu Xu, Mengying Yu, Lei Zhang, Weijie Hao, Zekun Guo   +7 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Circ-SAR1A Promotes Renal Cell Carcinoma Progression Through miR-382/YBX1 Axis

Cancer Management and Research, 2020
Xiaolei Zhao,* Zhenhua Zhao,* Wenchao Xu, Hui Liu, Junkai Chang, Weibo Xu, Song Li, Songqiang Cao, Junqing Hou Department of Urology, Huaihe Hospital of Henan University, Kaifeng 475000, People’s Republic of China*These authors contributed equally ...
Zhao X, Zhao Z, Xu W, Liu H, Chang J, Xu W, Li S, Cao S, Hou J   +8 more
doaj  

Isoimperatorin improves osteoporosis by increasing YBX1 expression to promote BGLAP m5C modification

Scientific Reports
Osteoporosis is a chronic metabolic bone disease that is prone to fractures. Isoimperatorin (ISO) has been shown to alleviate the bone loss in ovariectomized (OVX) rats.
Guang Hu, Jing Wen, Hao Yang, Kaiwei Zhang   +3 more
doaj   +1 more source

MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells

Cancer Management and Research, 2020
Fei Zhang,1 Chuanxin Duan,1 Shucheng Yin,2 Ying Tian1 1Department of Otolaryngology, Maternal and Child Health Care Hospital of Hubei Province and Women and Children’s Hospital of Hubei Province, Wuhan 430070, People’s Republic of China ...
Zhang F, Duan C, Yin S, Tian Y
doaj  

miR-379-5p Inhibited the Proliferation of Acute Myeloid Leukemia Cells Through Negative Regulation of YBX1

Turkish Journal of Hematology
Objective: Acute myeloid leukemia (AML) highly lethal hematological malignancy that is difficult to treat. This study aimed to clarify the molecular mechanisms of miR-379-5p in AML progression.
Huichao Wu, Lin Zhao, Huanyu Guo, Yingjie Xie, Jianhua Hu, Xinxia Tan   +5 more
doaj   +1 more source

Targeting YBX1‐m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma

Clinical and Translational Medicine
Background RNA 5‐methylcytosine (m5C) plays an important role in the progression of hepatocellular carcinoma (HCC). Dysregulation of ferroptosis is closely associated with HCC. However, the effect of the epigenetic mRNA m5C modification on ferroptosis in
Ouwen Li, Ke An, Han Wang, Xianbin Li, Yueqin Wang, Lan Huang, Yue Du, Nuo Qin, Jiasheng Dong, Jingyao Wei, Ranran Sun, Yong Shi, Yanjia Guo, Xiangyi Sun, Ying Yang, Yun‐Gui Yang, Quancheng Kan, Xin Tian   +17 more
doaj   +1 more source

YBX1 Expression Marks Proliferative Tumour States with Context-Dependent Genomic Instability: A Pan-Cancer Analysis. [PDF]

Int J Mol Sci
Wang S, Shafaei Pishabad Z, Sarkar D, Bhandarkar AA, Sarwar M, Jeffs A, Reid G, Braithwaite A, Mehta S.   +8 more
europepmc   +1 more source