Results 21 to 30 of about 7,882 (190)
YBX1 (Y box binding protein 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on YBX1 (Y box binding protein 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Evdokimova, V, Sorokin, A
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LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis [PDF]
International Journal of Molecular Sciences, 2020 Oral submucous fibrosis (OSF) has been recognized as a precancerous disorder in the oral cavity. Great effort has been made to inhibit the malignant progression of OSF over the past decades, but the cure of this fibrosis disease has not been discovered. In the present study, we found that a long noncoding RNA, LINC00312, was upregulated in OSF tissues,
Chuan-Hang Yu +6 more
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Ybx1 fine-tunes PRC2 activities to control embryonic brain development [PDF]
Nature Communications, 2020 AbstractChromatin modifiers affect spatiotemporal gene expression programs that underlie organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial chromatin modifier in executing neurodevelopmental programs. Here, we find that PRC2 interacts with the nucleic acid–binding protein Ybx1.
Myron K. Evans +8 more
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Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos
Frontiers in Cell and Developmental Biology, 2023 Y-box binding protein 1 (YBX1) plays important roles in RNA stabilization, translation, transcriptional regulation, and mitophagy. However, its effects on porcine preimplantation embryos remain unclear. In this study, we knocked down YBX1 in the one-cell
Wen-Jie Jiang +7 more
doaj +1 more source
Isoimperatorin improves osteoporosis by increasing YBX1 expression to promote BGLAP m5C modification
Scientific ReportsOsteoporosis is a chronic metabolic bone disease that is prone to fractures. Isoimperatorin (ISO) has been shown to alleviate the bone loss in ovariectomized (OVX) rats.
Guang Hu +3 more
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YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma
Frontiers in Oncology, 2021 Abnormal expression of the transcription factor Y-box-binding protein-1 (YBX1) is associated with the proliferation, migration, aggressiveness, and stem-like properties of various cancers.
Qiang Xie +17 more
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Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]
, 2017 RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M +6 more
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DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]
, 2017 Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong +6 more
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Transfer RNA-derived small RNAs in the cancer transcriptome [PDF]
, 2016 The cellular lifetime includes stages such as differentiation, proliferation, division, senescence and apoptosis.These stages are driven by a strictly ordered process of transcription dynamics.
A Dueck +38 more
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CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1 [PDF]
Signal Transduction and Targeted Therapy, 2020 AbstractSorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance significantly limits its therapeutic efficacy, and the mechanisms underlying resistance have not been fully clarified. Here we report that a circular RNA, circRNA-SORE (a circular RNA upregulated in sorafenib-resistant
Junjie Xu +13 more
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