Results 111 to 120 of about 258,986 (286)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Overview of systems and techniques for surface display of recombinant proteins in yeast S. cerevisiae

Applied Food Biotechnology, 2015
In the past decade much effort has been devoted to the development of new expression systems and novel techniques for the surface display of heterologous proteins in yeast in order to improve their applications in biotechnology, food technology ...
Renata Teparic, Vladimir Mrsa
doaj  

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, EarlyView.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source

Single-cell analysis of yeast surface display for designer cellulosome applications using a fluorescent protein complex

Microbiology Spectrum
Designer cellulosomes (DCs) are precisely engineered multi-enzyme complexes aimed at lignocellulose saccharification. Achieving spontaneous designer cellulosome display on yeast cell surfaces has been a long-term objective to enhance consolidated ...
Babette Lamote, Emma Cremelie, Kristel Demeyere, Philippe De Groote, Dennis Grimon, Julie Vanderstraeten, Evelyne Meyer, Marjan De Mey, Yves Briers   +8 more
doaj   +1 more source

The future of bioethanol [PDF]

, 2019
Yeasts have been domesticated by mankind before horses. After the mastering of alcoholic fermentation for centuries, yeasts have become the protagonist of one of the most important biotechnological industries worldwide: the production of bioethanol. This
Basso, Luiz C., Basso, Thiago O., Walker, Graeme M., Walker, Roy S.K.   +3 more
core  

Efficient Self‐Cleaning and Anti‐Bacterial Behavior Realized by Hierarchical Structure in Hybrid Waterborne Polyurethane Coatings Containing Photocatalyst

Advanced Materials Interfaces, EarlyView.
Hybrid WPU coatings with a hierarchical structure are constructed by first directional freezing polymerization of degradable hydrogels with a vertical channel structure and then filling these channels with aqueous WPU solution containing carbon nitride (g‐C3N4) nanosheets.
Xiaobei Zhou, Jing Xu, Jie Yu, Jie Liu, Meiqun Hu, Lie Zhao, Peter Müller‐Buschbaum, Dongming Qi, Qi Zhong   +8 more
wiley   +1 more source

Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin

Antibodies, 2019
Influenza B virus (IBV) circulates in the human population and causes considerable disease burden worldwide, each year. Current IBV vaccines can struggle to mount an effective cross-reactive immune response, as strains become mismatched, due to constant ...
Walter Ramage, Tiziano Gaiotto, Christina Ball, Paul Risley, George W. Carnell, Nigel Temperton, Chung Y. Cheung, Othmar G. Engelhardt, Simon E. Hufton   +8 more
doaj   +1 more source

Magnetically Actuated Drops‐on‐Stilts Microrobots for Transport and Delivery of Hydrophobic Cargo

Advanced Materials Interfaces, EarlyView.
Iron oxide nanoparticles and oil droplets in external magnetic fields form “drops‐on‐stilts” microrobots that transport hydrophobic cargo. Tunable nanoparticle–droplet interactions generate stilt‐like structures. Field rotation enables walking, obstacle navigation, and collective motion.
Oluwafemi Ligan, Hrishabh Singh, Sahil Kulkarni, Hong Huy Tran, James M. Kikkawa, Daeyeon Lee, Ravi Radhakrishnan, Edward Steager, Hyun Koo, Kathleen Stebe   +9 more
wiley   +1 more source

Exonuclease domain mutants of yeast DIS3 display genome instability

Nucleus, 2019
The exosome functions to regulate the cellular transcriptome through RNA biogenesis, surveillance, and decay. Mutations in Dis3, a catalytic subunit of the RNA exosome with separable endonuclease and exonuclease activities, are linked to multiple myeloma.
Karissa L. Milbury, Biplab Paul, Azra Lari, Claire Fowler, Ben Montpetit, Peter C. Stirling   +5 more
doaj   +1 more source