Bioadsorption Strategies with Yeast Molecular Display Technology
Molecular display techniques using microbial cell surfaces have been widely developed in the past twenty years, and are useful tools as whole cell catalysts for various applications such as bioconversion, bioremediation, biosensing, and the screening system of protein libraries.
Seiji, Shibasaki, Mitsuyoshi, Ueda
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Expansive evolution of the TREHALOSE-6-PHOSPHATE PHOSPHATASE gene family in Arabidopsis [PDF]
Trehalose is a nonreducing sugar used as a reserve carbohydrate and stress protectant in a variety of organisms. While higher plants typically do not accumulate high levels of trehalose, they encode large families of putative trehalose biosynthesis genes.
Avonce, Nelson +10 more
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Prompting Fab Yeast Surface Display Efficiency by ER Retention and Molecular Chaperon Co-expression. [PDF]
For antibody discovery and engineering, yeast surface display (YSD) of antigen-binding fragments (Fabs) and coupled fluorescence activated cell sorting (FACS) provide intact paratopic conformations and quantitative analysis at the monoclonal level, and ...
Ge, Xin +7 more
core
Application of Random Matrix Theory to Biological Networks
We show that spectral fluctuation of interaction matrices of yeast a core protein interaction network and a metabolic network follows the description of the Gaussian orthogonal ensemble (GOE) of random matrix theory (RMT).
Barabasi +24 more
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Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid +2 more
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Yeast Surface Display of Lamprey Variable Lymphocyte Receptors [PDF]
The variable lymphocyte receptors (VLRs) of lamprey and hagfish comprise leucine-rich repeat modules, instead of the immunoglobulin-like domain building blocks of antibodies and T-cell receptors in jawed vertebrates. Both types of vertebrate-rearranging antigen receptors are similarly diverse, with repertoires that can potentially exceed 10(14) unique ...
Gang, Xu, Satoshi, Tasumi, Zeev, Pancer
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Stress-induced nuclear accumulation is dispensable for Hog1-dependent gene expression and virulence in a fungal pathogen [PDF]
The authors thank E. Veal for intellectual input. This work was funded by the UK Biotechnology and Biological Research Council [J.Q. BB/K016393/1; A.J.P.B.
Brown, Alistair J P +4 more
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Mrpl35, A Mitospecific Component of Mitoribosomes, Plays A Key Role in Cytochrome \u3cem\u3eC\u3c/em\u3e Oxidase Assembly [PDF]
Mitoribosomes perform the synthesis of the core components of the oxidative phosphorylation (OXPHOS) system encoded by the mitochondrial genome.
Box, Jodie M +2 more
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Escherichia coli surface display for the selection of nanobodies
Summary Nanobodies (Nbs) are the smallest functional antibody fragments known in nature and have multiple applications in biomedicine or environmental monitoring.
Valencio Salema, Luis Ángel Fernández
doaj +1 more source
Structural patterns in complex networks through spectral analysis [PDF]
The study of some structural properties of networks is introduced from a graph spectral perspective. First, subgraph centrality of nodes is defined and used to classify essential proteins in a proteomic map.
Estrada, Ernesto
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