Results 31 to 40 of about 258,986 (286)
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity [PDF]
, 2020 Malaria is a global health concern and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum ...
Bosch, A. +15 more
core +2 more sources
Selection and characterization of FcεRI phospho-ITAM specific antibodies
mAbs, 2019 Post-translational modifications, such as the phosphorylation of tyrosines, are often the initiation step for intracellular signaling cascades. Pan-reactive antibodies against modified amino acids (e.g., anti-phosphotyrosine), which are often used to ...
Nileena Velappan +10 more
doaj +1 more source
Smc5/6: a link between DNA repair and unidirectional replication? [PDF]
, 2008 Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada +46 more
core +1 more source
A model of large-scale proteome evolution [PDF]
, 2002 The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have shown that its
Kepler, Thomas B. +3 more
core +3 more sources
Yeast surface display-based microfluidic immunoassay
Sensors and Actuators B: Chemical, 2012 In this paper, we present a new microfluidic immunoassay platform, which is based on the synergistic combination of the yeast surface display (YSD) technique and the microfluidic technology. Utilizing the YSD technique, antigens specific to the target antibody are displayed on the surface of engineered yeast cells with intracellular fluorescent ...
Wang, Jing +5 more
openaire +3 more sources
Global transposable characteristics in the yeast complete DNA sequence [PDF]
, 2010 Global transposable characteristics in the complete DNA sequence of the Saccharomyces cevevisiae yeast is determined by using the metric representation and recurrence plot methods.
Wu, Zuo-Bing
core +2 more sources
Yeast Display of Engineered Antibody Domains [PDF]
, 2012 Yeast display is an efficient technology for selection of antibodies and other proteins with high affinity and thermal stability. Here, we describe a method for affinity maturation of engineered antibody domains (eAds) using yeast display. EAd yeast libraries of relatively large size (∼10⁹) were generated and subjected to alternating rounds of magnetic-
Qi, Zhao +2 more
openaire +2 more sources
Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes [PDF]
, 2006 ISWI proteins form the catalytic core of a subset of ATP-dependent chromatin remodelling activities in eukaryotes from yeast to man. Many of these complexes have been found to reposition nucleosomes, but with different directionalities.
Alen +33 more
core +4 more sources
The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence [PDF]
, 2016 Funding: This work was funded by the European Research Council [http://erc.europa.eu/], AJPB (STRIFE Advanced Grant; C-2009-AdG-249793). The work was also supported by: the Wellcome Trust [www.wellcome.ac.uk], AJPB (080088, 097377); the UK Biotechnology ...
A Brand +75 more
core +4 more sources
Toxins, 2014 Staphylococcus aureus and group A Streptococcus secrete a collection of toxins called superantigens (SAgs), so-called because they stimulate a large fraction of an individual’s T cells.
Preeti Sharma +2 more
doaj +1 more source