Results 111 to 120 of about 111,329,672 (189)

Yin Yang 1 (YY1)-induced long intergenic non-protein coding RNA 472 (LINC00472) aggravates sepsis-associated cardiac dysfunction via the micro-RNA-335-3p (miR-335-3p)/Monoamine oxidase A (MAOA) cascade.

Bioengineered, 2022
Mo G, Mo J, Tan X, Wang J, Yan Z, Liu Y.
europepmc   +1 more source

Therapeutic Implications of Targeting YY1 in Glioblastoma

The transcription factor Yin Yang 1 (YY1) plays a pivotal role in the pathogenesis of glioblastoma multiforme (GBM), an aggressive form of brain tumor.
Inesa Navasardyan, Apostolos Zaravinos, Benjamin Bonavida   +2 more
core   +1 more source

Hybrid 18F-FDG-PET/MRI Measurement of Standardized Uptake Value Coupled with Yin Yang 1 Signature in Metastatic Breast Cancer. A Preliminary Study

, 2019
Detection of breast cancer (BC) metastasis at the early stage is important for the assessment of BC progression status. Image analysis represents a valuable tool for the management of oncological patients.
Franzese Monica, Soricelli Andrea, Salvatore Marco, Garbino Nunzia, de Nigris Filomena, Napoli Claudio, SCHIANO, Concetta, Schiano Concetta, Pane Katia   +8 more
core   +1 more source

Yin Yang 1 is a critical regulator of B-cell development

, 2007
The role of the transcription factor Yin Yang 1 (YY1) in development is largely unknown. Here we show that specific ablation of YY1 in mouse B cells caused a defect in somatic rearrangement in the immunoglobulin heavy-chain (IgH) locus and a block in the
Hobeika, E., Skok, J., Shi, Y., Schmidt-Supprian, M., Jumaa, H., Rajewsky, K., Liu, H., Barteneva, N., Reth, M., Pelanda, R.   +9 more
core  

Chromatin factor YY1 controls fetal hematopoietic stem cell migration and engraftment in mice

The Journal of Clinical Investigation
The fetal liver is the primary site of hematopoietic stem cell (HSC) generation during embryonic development. However, the molecular mechanisms governing the transition of hematopoiesis from the fetal liver to the BM remain incompletely understood. Here,
Sahitya Saka, Zhanping Lu, Yinghua Wang, Peng Liu, Deependra K. Singh, Junki P. Lee, Carmen G. Palii, Tyler R. Alvarez, Anna L.F.V. Assumpção, Xiaona You, Jing Zhang, Marjorie Brand, Michael L. Atchison, Xuan Pan   +13 more
doaj   +1 more source

Yin Yang 1 contains G-quadruplex structures in its promoter and 5′-UTR and its expression is modulated by G4 resolvase 1 [PDF]

, 2017
Yin Yang 1 (YY1) is a multifunctional protein with regulatory potential in tumorigenesis. Ample studies demonstrated the activities of YY1 in regulating gene expression and mediating differential protein modifications.
Cao, Paul, Zhang, Qiang, Stadelman, Kristin, Lei, Ming, Wan, Meimei, Miller, Lance D., Nagamine, Yoshikuni, Smaldino, Philip J., Giri, Banabihari, Sui, Guangchao, Huang, Weiwei, Vaughn, James P., Akman, Steven A.   +12 more
core  

Lactate Induces Tumor Progression via LAR Motif-Dependent Yin-Yang 1 Degradation

The metabolic reprogramming of aerobic glycolysis contributes to tumorigenesis. High plasma lactate is a critical regulator in the development of many human malignancies; however, the underlying molecular mechanisms of cancer progression in response to ...
Wang, Junwen, Cai, Qiliang, Chen, Xiaoting, Li, Ying, Wei, Fang, Wang, Yuyan, Tong, Yin, Gao, Shujun, Han, Xiao, Du, Shujuan, Zhu, Caixia, Yu, Dan   +11 more
core   +1 more source

YY1 in hematopoietic stem cells: epigenetic regulation, chromatin architecture, and aging. [PDF]

Curr Opin Hematol
Wang Y, Pan X.
europepmc   +1 more source

INO80E Suppresses Oxidized LDL-Induced Endothelial Apoptosis Through HDAC1-Mediated Stabilization of YY1. [PDF]

Biomolecules
Liu T, Luo Q, Yang S, Yang D, Lv X, Zhao L, Tuo Q.   +6 more
europepmc   +1 more source

YY1 Suppresses Tumor Growth by Negatively Regulating the Expression and Translation Activity of eIF4E in Nasopharyngeal Carcinoma. [PDF]

Cancers (Basel)
Duan Y, Zhou X, Wei J, Xue C, Zheng L, Zeng T, Deng H, Fan S, Xiong W, Zhou M, Peng S, Li M.   +11 more
europepmc   +1 more source