Results 71 to 80 of about 14,193 (213)

Rebreeding of Female Mountain Lions After Litter Mortality

Ecology and Evolution, Volume 16, Issue 4, April 2026.
We documented rapid rebreeding by female mountain lions (Puma concolor) following litter loss, including the shortest known rebreeding interval to date. These observations highlight the importance of infanticide and intraguild competition in shaping female fitness and population dynamics.
Mark A. Peyton, Brian D. Jansen, James W. Cain III, Jonathan A. Jenks   +3 more
wiley   +1 more source

Suppression of osteoclastogenesis via α2-adrenergic receptors [PDF]

, 2018
The sympathetic nervous system is known to regulate osteoclast development. However, the involvement of α2-adrenergic receptors (α2-ARs) in osteoclastogenesis is not well understood.
Chen, Andy, Goto, Shigemi, Hamajima, Kosuke, Hamamura, Kazunori, Hirai, Takao, Ishizuka, Kyoko, Kodama, Daisuke, Kondo, Hisataka, Miyazawa, Ken, Mori, Hironori, Tanaka, Kenjiro, Togari, Akifumi, Yo, Shoyoku, Yokota, Hiroki   +13 more
core   +1 more source

Context‐Dependent Extinction and Return of Pavlovian Alcohol‐Seeking Behavior in Male and Female Rats

Alcohol, Clinical and Experimental Research, Volume 50, Issue 4, April 2026.
Alcohol‐associated cues renewed conditioned alcohol seeking when rats returned to the original conditioning context after extinction. Male and female rats showed comparable cue‐elicited approach and sipper contact, suggesting shared contextual memory retrieval mechanisms underlying relapse‐like behavior.
Taylor A. Simmons, Anagha Deshpande, Alicia R. Daley, Alexander J. Etz, Rueben A. Gonzales, Marie H. Monfils, Hongjoo J. Lee   +6 more
wiley   +1 more source

The effects of clonidine and yohimbine in the tail flick and hot plate tests in the naked mole rat (Heterocephalus glaber)

BMC Research Notes, 2021
Objective The naked mole rat (NMR) (Heterocephalus glaber) is increasingly considered an important biomedical research model for various conditions like hypoxic brain injury, cancer and nociception.
R. M. Mwobobia, T. I. Kanui, K. S. P. Abelson   +2 more
doaj   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, Volume 38, Issue 4, Page 220-228, April 2026.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Sleep loss and recovery after administration of drugs related to different arousal systems in rats [PDF]

, 2016
Sleep is homeostatically regulated suggesting a restorative function. Sleep deprivation is compensated by an increase in length and intensity of sleep.
Détári, L, Hajnik, T, Pethő, M, Szalontai, Ö, Tóth, A   +4 more
core   +1 more source

USE OF HERBAL MEDICINES IN PSYCHIATRY

Zdravniški Vestnik, 2001
Background. »Lost illusions« about conventionalmedicine, together with the orientation towards the »natural«way of life, lead into ever increasing use of alternative or complementaryways of treatment.
Blanka Kores Plesničar, Barbara Razinger Mihovec   +1 more
doaj  

Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in Wistar rats [PDF]

, 2015
Background and Purpose: Substance P and its preferred neurokinin receptor NK1 have been implicated in stress and anxiety and have been proposed as possible therapeutic targets for the treatment of anxiety/depression.
Abercrombie, Aggleton, Aghajanian, Alexander, Asadi, Belknap, Borhegyi, Bremner, Bremner, Choi, Ciccocioppo, Ciccocioppo, Ciccocioppo, Ciccocioppo, Cippitelli, Cippitelli, Dayas, Ebner, Ebner, Ebner, Eichenbaum, Engin, George, Gosnell, Gozzi, Hamke, Hansson, Hansson, Holmberg, Kilkenny, Koob, Koob, Koob, LeDoux, Liu, Maeno, Marinelli, Martin-Fardon, McGrath, McLean, Nakamura, Nakaya, Ogier, Pacak, Pawson, Paxinos, Quartara, Ribeiro-da-Silva, Roberts, Santarelli, Schank, Schank, Schank, Schank, Schank, Siegel, Singewald, Steensland, Thorsell, Ubaldi, Umhau, Volkow   +61 more
core   +1 more source

Caffeine Content Assessment in Beverages and Food Supplements: Regulatory Challenges and Health Implications

ChemFoodChem, Volume 2, Issue 1, March 2026.
ABSTRACT This study presents an analysis of caffeine content in food supplements and evaluates current regulatory frameworks against established safety guidelines. High‐caffeine products, particularly sports, and food supplements, were assessed for compliance with the safety opinion of the European Food Safety Authority (EFSA). The investigation during
Leonie Rinke, Ann‐Kathrin Kull, Verena Bock, Dirk W. Lachenmeier   +3 more
wiley   +1 more source

An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse. [PDF]

, 2018
Tobacco use disorder is the leading cause of disease and preventable death worldwide, but current medications that are based on pharmacodynamics have low efficacy.
George, Olivier, Janda, Kim D, Kallupi, Marsida, Xue, Song, Zhou, Bin   +4 more
core   +1 more source