Results 101 to 110 of about 9,464 (261)

Investigating the fate of Zirconium-89 labelled antibody in cynomolgus macaques

Nuclear Medicine and Biology
Preclinical pharmacokinetic studies of therapeutic antibodies in non-human primates are desired because of the difficulty in extrapolating ADME data from animal models to humans. We evaluated the pharmacokinetics of 89Zr (Zirconium-89) -labelled anti-KLH human IgG and its metabolites to confirm their non-specific/physiological accumulation in healthy ...
Takanori, Sasaki, Sadaaki, Kimura, Akihiro, Noda, Yoshihiro, Murakami, Sosuke, Miyoshi, Masaru, Akehi, Kazuhiko, Ochiai, Masami, Watanabe, Takahiro, Higuchi, Eiji, Matsuura   +9 more
openaire   +3 more sources

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Image Guided Biodistribution and Pharmacokinetic Studies of Theranostics [PDF]

, 2012
Image guided technique is playing an increasingly important role in the investigation of the biodistribution and pharmacokinetics of drugs or drug delivery systems in various diseases, especially cancers.
Ding, Hong, Wu, Fang
core   +1 more source

From the Discovery of the Giant Magnetocaloric Effect to the Development of High‐Power‐Density Systems

Advanced Materials Technologies, EarlyView.
The article overviews past and current efforts on caloric materials and systems, highlighting the contributions of Ames National Laboratory to the field. Solid‐state caloric heat pumping is an innovative method that can be implemented in a wide range of cooling and heating applications.
Agata Czernuszewicz, Yaroslav Mudryk, Jun Cui, Lucas Griffith, Duane D. Johnson, Julie Slaughter   +5 more
wiley   +1 more source

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells [PDF]

, 2018
Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival.
Anushka Dongre, Atul Bhan, Baumeister, Brian Bierie, Camille LeGall, Chen, Curran, Dougan, Dranoff, D’Huyvetter, Forrester, Gijsbert M. Grotenbreg, Guimaraes, Guy, Hidde L. Ploegh, Hogquist, Holst, Holzinger, James Gorman, Jessica R. Ingram, Juan J. Cragnolini, Katherine A. Whang, Kawai, Knowles, Kourie, Larkin, Li, Li, Mall, Marigo, McCracken, McNamee, Michael Dougan, Mohammad Rashidian, Mombaerts, Monica Gostissa, Movahedi, Pardon, Quezada, Rashidian, Rashidian, Rashidian, Robert A. Weinberg, Saerens, Sato, Sockolosky, Tavaré, Theile, Van Elssen, Vegt, Vesely, Vosjan, Weissleder, Witte, Wu, Yamada   +55 more
core   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Design of feasibility study for the establishment of production of zirconium-89 radioisotope and implementation of 89Zr-radiopharmaceuticals in clinical practice in the Republic of North Macedonia [PDF]

, 2023
The radiopharmaceuticals based on zirconium-89 (89Zr) radiometal, in the last decade, have increased application in both preclinical and clinical studies.
Angelovska, Bistra, Atanasova, Marija, Cocevska, Maja, Jolevski, Filip, Kolevska, Katerina, Memeti, Shaban, Tripunoski, Toni, Ugrinska, Ana, Velickovska, Maja   +8 more
core  

Record High Polarization at 2 V and Imprint‐Free Operation in Superlattice HfO2‐ZrO2 by Proper Tuning of Ferro and Antiferroelectricity

Advanced Materials Technologies, EarlyView.
Low‐power ferroelectric capacitors, based on superlattice HfO2‐ZrO2 is reported. With proper tuning of ferro and antiferroelectricity, an imprint‐free high switchable polarization charge (2Pr of 76 µC/cm2) is obtained with 2MV/cm leading to linear analog weight update and non‐volatile retention, providing a design guideline for emerging non‐volatile ...
Xinye Li, Padma Srivari, Mari Honkanen, Turkka Salminen, Sayani Majumdar   +4 more
wiley   +1 more source

Advances in Solid‐Phase Processing Techniques: Innovations, Applications, and Future Perspectives

Advanced Materials Technologies, EarlyView.
Based on practical manufacturing challenges, this review examines advanced solid‐phase processing techniques that overcome the inherent limitations of conventional melting‐based and traditional solid‐phase manufacturing, enabling the production of higher‐performance components at reduced cost through process innovation and improved supply‐chain ...
Tianhao Wang
wiley   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source