Results 81 to 90 of about 9,464 (261)

Zirconium-89 labeled panitumumab: a potential immuno-PET probe for HER1-expressing carcinomas [PDF]

Nuclear Medicine and Biology, 2013
Anti-HER1 monoclonal antibody (mAb), panitumumab (Vectibix) is a fully human mAb approved by the FDA for the treatment of epidermal growth factor receptor (EGFR, HER1)-expressing colorectal cancers. By combining the targeted specificity of panitumumab with the quantitative in vivo imaging capabilities of PET, we evaluated the potential of (89)Zr-DFO ...
Sibaprasad, Bhattacharyya, Karen, Kurdziel, Ling, Wei, Lisa, Riffle, Gurmeet, Kaur, G Craig, Hill, Paula M, Jacobs, James L, Tatum, James H, Doroshow, Joseph D, Kalen   +9 more
openaire   +2 more sources

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

Immuno-PET Imaging of Siglec-15 Using the Zirconium-89-Labeled Therapeutic Antibody, NC318

Molecular Imaging, 2023
Objective. Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is overexpressed in various cancers which has led to the development of therapeutic anti-Siglec-15 monoconal antibodies (mAbs).
Elaine M. Jagoda, Falguni Basuli, Colleen Olkowski, Ido Weiss, Tim E. Phelps, Karen Wong, Anita Thien Ton, Kelly C. Lane, Steve Adler, Donna Butcher, Elijah F. Edmondson, Sol Langermann, Peter L. Choyke   +12 more
doaj   +1 more source

Development of an in vivo phosphorylation system in Escherichia coli [PDF]

, 2013
Recently, new strategies emerged in the field of monoclonal antibodies radiolabeling for PET imaging with the use of positron emitter such as zirconium-89 (89Zr, t½=78.4h) or gallium-68 (68Ga, t½=1.13h)[a]. Despite their important role in the therapeutic
Goux, Marine
core  

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, EarlyView.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

Immuno-positron emission tomography with zirconium-89-labeled monoclonal antibodies in oncology

Frontiers in Pharmacology, 2016
Selection of the right drug for the right patient is a promising approach to increase clinical benefit of targeted therapy with monoclonal antibodies (mAbs).
Yvonne W.S. Jauw, C. Willemien Menke-van der Houwen van Oordt, Otto S. Hoekstra, N. Harry Hendrikse, Danielle J. Vugts, Josee M. Zijlstra, Marc C. Huisman, Guus A.M.S. van Dongen   +7 more
doaj   +1 more source

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi, Maria Sabrina Sarto   +7 more
wiley   +1 more source

Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27) [PDF]

, 2018
Aims/hypothesis: Non-invasive diagnostic tools specific for pancreatic beta cells will have a profound impact on our understanding of the pathophysiology of metabolic diseases such as diabetes.
Danzer, C., Dikaiou, K., Esterhazy, D., Fischer, E., Honer, M., Keist, R., Krek, W., Matile, H., Migliorini, C., Ripoll, J., Rudin, M., Schibli, R., Stoffel, M., Stuker, F., Vats, D., Wang, H.   +15 more
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Triple negative breast cancer: nanosolutions for a big challenge [PDF]

, 2015
Triple negative breast cancer (TNBC) is a particular immunopathological subtype of breast cancer that lacks expression of estrogen and progesterone receptors (ER/PR) and amplification of the human epidermal growth factor receptor 2 (HER2) gene ...
Adams, Aebi, Ahn, Ali, Almuhaideb, Arpino, Awada, Ayala-Orozco, Bar, Baselga, Baselga, Baselga, Bauer, Bawarski, Bertos, Bianco, Boyle, Brigger, Brown, Burke, Burstein, Cardoso, Carey, Chen, Chen, Cho, Crisp, Crown, Dai, Davis, DeNardo, Dent, Dogan, Duncan, Engebraaten, Fauzee, Feng, Ferrari, Ferraro, Finlay, Franchina, Ghosh, Goldhirsch, Gonzalez-Angulo, Gref, Grobmyer, Gu, Hammond, Herranz, Hirsch, Hong, Huang, Hun, Hussein, Iida, Inoue, Jain, Jain, Jin, Johnstone, Joshi, Julien, Kadioglu, Kang, Kaur, Kircher, Ko, Krag, Kucuk, Kutty, Kutty, Lainé, Lamprecht, Lay, LeBeau, Lee, Lehmann, Li, Liu, Ljubimova, Ljubimova, Lund, Lyshchik, Ma, Ma, Maeda, Matsumura, Matsumura, Meier, Meng, Mikhail, Mittapalli, Montagna, Mura, O'Toole, Oakman, Ossovskaya, Owens, Palma, Park, Passarella, Passarella, Penault-Llorca, Raha, Raoof, Reubi, Rodrigues, Rodrigues, Rousseau, Sahoo, Schmadeka, Sharma, Sharma, Shi, Shi, Siegel, Svenson, Tacar, Tan, Taurin, Tekedereli, Thomas, Tinoco, Tobio, Torchilin, Tran, Turner, van Scheltinga, van Scheltinga, Wang, Wang, Yu, Yu, Zhu   +133 more
core   +1 more source