Results 161 to 170 of about 59,731 (190)

ZO-1 regulates Hippo-independent YAP activity and cell proliferation via a GEF-H1- and TBK1-regulated mechanosensitive signalling network

, 2023
Haas AJ, Karakus M, Zihni C, Balda MS, Matter K.   +4 more
europepmc   +1 more source

A secured cloud‐medical data sharing with A‐BRSA and Salp ‐Ant Lion Optimisation Algorithm

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Sharing medical data among healthcare providers, researchers, and patients is crucial for efficient healthcare services. Cloud‐assisted smart healthcare (s‐healthcare) systems have made it easier to store EHRs effectively. However, the traditional encryption algorithms used to secure this data can be vulnerable to attacks if the encryption key
Adel Binbusayyis, Abed Alanazi, Shtwai Alsubai, Areej Alasiry, Mehrez Marzougui, Abdullah Alqahtani, Mohemmed Sha, Muhammad Aslam   +7 more
wiley   +1 more source

ZO-1 boosts the in vitro self-renewal of pre-haematopoietic stem cells from OCT4-reprogrammed human hair follicle mesenchymal stem cells through cytoskeleton remodeling. [PDF]

Stem Cell Res Ther
Ruan Y, Huang X, Sun P, Yu X, Tan X, Song Y, Chen H, Liu Z.   +7 more
europepmc   +1 more source

Single‐Cell Omics Analysis of Human Basophils Reveals Two Transcriptionally Distinct Populations

Allergy, EarlyView.
Integrated single‐cell transcriptomics and large‐scale immunophenotyping reveal the molecular landscape of human basophils. Circulating basophils comprise two transcriptionally distinct populations. A user‐friendly web resource enables interactive exploration of the generated data.
Sofia Papavasileiou, Jiezhen Mo, Daryl Boey, Chenyan Wu, Magnus Tronstad, Lucille Margerie, Remi‐André Olsen, Jörg A. Bachmann, Jing Hui Low, Jocelyn Ong, Lars Heede Blom, Anand Kumar Andiappan, Gunnar Nilsson, Joakim S. Dahlin   +13 more
wiley   +1 more source

Fluvoxamine may reverse the decrease in filtering capacity that occurs in acute kidney injury by increasing IL-10 and ACE expressions and preserving AQ-2, AQ-4, CL-5, and ZO-1 expressions. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Karakuyu NF, Camlica T, Asci H, Milletsever A, Ulusoy A, Gonuler FM, Altuntas A.   +6 more
europepmc   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

The Scribble-SGEF-Dlg1 complex regulates E-cadherin and ZO-1 stability, turnover and transcription in epithelial cells.

J Cell Sci
Rabino A, Awadia S, Ali N, Edson A, Garcia-Mata R.   +4 more
europepmc   +1 more source

circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. [PDF]

Cell Biol Toxicol
Liu Y, Qin Y, Zhang Y.
europepmc   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Biallelic MYH3 Variants Cause Distal Arthrogryposis in Compound Heterozygosity and a Subclinical Phenotype in Simple Heterozygosity. Codominance or Recessive Inheritance?

Clinical Genetics, EarlyView.
A nuclear family affected by distal arthrogryposis with novel biallelic MYH3 variants, which at the heterozygous state yield a subclinical phenotype, highlighting the complexity of MYH3‐related disorders and their inheritance modes. ABSTRACT Distal arthrogryposis constitutes a highly heterogeneous group of disorders with a critical need for clear ...
Omar Zgheib, Thomas Rio‐Frio, Michel Guipponi, Thierry Nouspikel, Siv Fokstuen, Marc Abramowicz, Philippe Khau Van Kien   +6 more
wiley   +1 more source