Results 131 to 140 of about 17,751,190 (266)

zo-2 gene alternative promoters in normal and neoplastic human pancreatic duct cells

, 1999
International audienceWe have observed that 2 forms of zonula occludens 2 (ZO-2) protein, ZO-2A and ZO-2C, are expressed in normal human pancreatic duct cells, but only ZO-2C in pancreatic duct adenocarcinoma.
Talamonti, Mark, Scarpelli, Dante, Engeriser, J. Luke, Koutnikova, Hanna, Tsao, Ming-Sound, Chlenski, Alexandre, Oyasu, Ryoichi, Ketels, Kathleen   +7 more
core   +1 more source

ApoE‐ and Cfh‐deficient mice exhibit structural and molecular features of human early–intermediate retinal degeneration

Animal Models and Experimental Medicine, EarlyView.
Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde, Maite Moreno Orduña, Jaione Bezunartea, Idoia Belza, Ainara Chas, Laura Fernández‐Sánchez, Nicolás Cuenca Navarro, Alfredo García‐Layana, Patricia Fernández‐Robredo, María Hernández   +9 more
wiley   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

The Role of Intraparticle Diffusion in Kinetic Model Discrimination: Proof of Concept Testing for Methanol Dehydration

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The rate of a heterogeneous catalytic process may simultaneously be described by several rate equations. In this case, discrimination between the plausible kinetic models is required. An intrinsic kinetic model of a heterogeneous catalytic process may successively be discriminated by the transition from a reaction rate‐limited regime to an ...
Oleksii Zhokh, Andrii Trypolskyi, Peter Strizhak   +2 more
wiley   +1 more source

Efficacy and safety of peppermint oil for the treatment in Japanese patients with irritable bowel syndrome: a prospective, open-label, and single-arm study

BioPsychoSocial Medicine
Background In Europe, an herbal medicine containing peppermint oil is widely used in patients with irritable bowel syndrome (IBS). In Japan, however, no clinical evidence for peppermint oil in IBS has been established, and it has not been approved as a ...
Kei Matsueda, Shin Fukudo, Masayuki Ogishima, Yuki Naito, Soichiro Nakamura   +4 more
doaj   +1 more source

ZO-2 favors Hippo signaling, and its re-expression in the steatotic liver by AMPK restores junctional sealing. [PDF]

Tissue Barriers, 2022
González-González L, Gallego-Gutiérrez H, Martin-Tapia D, Avelino-Cruz JE, Hernández-Guzmán C, Rangel-Guerrero SI, Alvarez-Salas LM, Garay E, Chávez-Munguía B, Gutiérrez-Ruiz MC, Hernández-Melchor D, López-Bayghen E, González-Mariscal L.   +12 more
europepmc   +1 more source

Private omgevingsparticipatie, maar dan met de gemeente: zo doe je dat

, 2022
TU Delft-onderzoeker Wouter Jan Verheul onderzocht van 15 gemeenten hun handreikingen voor participatie door private initiatiefnemers. Zo brengt hij in kaart wat de verhouding is tussen private en publieke partijen bij omgevingsparticipatie.Urban ...
Verheul, W.J. (author)
core  

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Why people participate in online political crowdfunding: A civic voluntarism perspective

, 2019
Digital technology allows people to participate in various social activities easily. In politics, online crowdfunding has been gaining attention because it gives politicians benefits to raise political funds from the public.
Zo, Hangjung, Kusumarani, Riri
core   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source