Results 111 to 120 of about 24,539,782 (228)

Expression and Clinical Significance of ZO-1 in Patients with Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2011
Background and objective It has been proven that the expression of ZO-1 (zonula occluden-1) was correlated with the growth and metastasis of cancer.
Yekai WANG   +5 more
doaj  

Transcriptomic Analysis of Tight Junction Proteins Demonstrates the Aberrant Expression and Function of Zona Occludens 2 (ZO-2) Protein in Stanford Type A Aortic Dissection. [PDF]

open access: yesJ Pers Med, 2023
Magouliotis DE   +9 more
europepmc   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu   +20 more
wiley   +1 more source

E12.5 mouse dorsal cortex, Itgb1 KD, R-Ras(38V) OE and mInsc OE, EGFP-ZO-1, mem-CyRFP

open access: yes, 2019
Additional time-lapse movies for Figure 5 e,f. E12.5 mouse dorsal cortex, Itgb1 KD, R-Ras(38V) OE and mInsc OE, EGFP-ZO-1, mem-CyRFP.
Atsunori Shitamukai (7859580)   +1 more
core   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Increased ZO-2 levels promote cell migration.

open access: yes, 2016
Ablation of ZO-2 expression reduces wound healing ability in HeLa cells, to a similar degree as ablation of E6 expression. (A). Confluent HeLa cells were scratched with a plastic pipette tip 48h after being transfected with si-RNA to luciferase, HPV 18 ...
Michael P. Myers (31172)   +4 more
core   +1 more source

Insights Into the Nature of Quantum Emitters in Electron‐Irradiated Hexagonal Boron Nitride

open access: yesAdvanced Science, EarlyView.
Hyperspectral imaging is used to identify quantum emitters hosted by the 2D material hexagonal boron nitride. By selecting specific emission wavelengths, one can distinguish individual emitters from ensembles and gain important insights into the atomic structure of these emitters.
Mouli Hazra   +12 more
wiley   +1 more source

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