Results 111 to 120 of about 17,751,190 (266)
Advanced Science, EarlyView.Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu +8 more
wiley +1 more source
A promising protein responsible for overactive bladder in ovariectomized mice
Taiwanese Journal of Obstetrics & Gynecology, 2017 Objective: Ovariectomy (OVX) in mice is a model mimicking a neuro-electronic proof of an overactive bladder in postmenopausal women. Overactive bladder (OAB) was recently found to be due to an altered gap junction protein in a rat model. Thus, this study
Huey-Yi Chen +4 more
doaj +1 more source
Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety‐Like Behaviors
Advanced Science, EarlyView.ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Zhigang Chen, Xing Li
wiley +1 more source
E12.5 mouse dorsal cortex, R-Ras KO, NICD OE and mInsc OE, EGFP-ZO-1, mem-CyRFP
, 2019 Additional time-lapse movies for Figure 5j,k. E12.5 mouse dorsal cortex, R-Ras KO, NICD OE and mInsc OE, EGFP-ZO-1, mem-CyRFP. Z-projection images.
Atsunori Shitamukai (7859580) +1 more
core +1 more source
Advanced Science, EarlyView.A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source
Biochemical and Biophysical Research Communications, 1998 The tight junction is composed of many proteins and includes three members of the MAGUK (membrane-associated, guanylate kinase-like) protein family: ZO-1, ZO-2, and ZO-3. ZO-2 was cloned and sequenced from embryonic chicken retina. Antibodies against a short ZO-2 peptide immunolabeled the outer limiting membrane (an adherens junction of the neural ...
J R, Collins, L J, Rizzolo
openaire +2 more sources
E12.5 mouse dorsal cortex, Itgb1 KD, R-Ras(38V) OE and mInsc OE, EGFP-ZO-1, mem-CyRFP
, 2019 Additional time-lapse movies for Figure 5 e,f. E12.5 mouse dorsal cortex, Itgb1 KD, R-Ras(38V) OE and mInsc OE, EGFP-ZO-1, mem-CyRFP.
Atsunori Shitamukai (7859580) +1 more
core +1 more source
Advanced Science, EarlyView.An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang +8 more
wiley +1 more source