Results 231 to 240 of about 17,751,190 (266)

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

open access: yesCell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang   +10 more
wiley   +1 more source

Morin inhibits fructose bisphosphate aldolase activity and resists Cryptosporidium parvum infection. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist
Chen M   +11 more
europepmc   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

Protein Corona‐Coated Crystal Silica From Sandstorms Amplifies Allergic Rhinitis by Regulating Epithelial Integrity in Mice and Human Nasal Epithelia

open access: yes
Allergy, EarlyView.
Cuishuang Dong   +9 more
wiley   +1 more source

Natural Parasitism of Nezara viridula (Linnaeus) (Hemiptera: Pentatomidae) by Trichopoda pictipennis Bigot (Diptera: Tachinidae) in an Organic Strawberry Field in Germany

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Natural parasitism of the invasive southern green stinkbug was recorded in an organic strawberry cropping system in southwestern Germany. The tachinid fly Trichopoda pictipennis shows successful establishment and field activity, indicating ongoing range expansion.
Sophie Wenz   +2 more
wiley   +1 more source

Harnessing Polygenic Risk Scores to Refine Venous Thromboembolism Risk Stratification

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Venous thromboembolism (VTE) is a major cause of morbidity in patients of all ages. Despite growing interest in polygenic risk scores (PRS) for VTE, their utility remains understudied. Our objective was to evaluate the independent impact of a PRS on VTE susceptibility in adults and children.
Katlyn G. McKay   +7 more
wiley   +1 more source

Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway. [PDF]

open access: yesPLoS One
Lv Y   +14 more
europepmc   +1 more source

Ultrafast python‐integrated single‐entity electrochemical sensor for detecting glycated albumin

open access: yesThe FEBS Journal, EarlyView.
Traditional biosensors suffer from the fact that recognition receptors are immobilised and that they denature on electrodes. Instead here we use receptors freely in solution, minimising surface compression and preserving activity to boost signal efficiency. Python‐driven processing turns the electrochemical response into a rapid, robust readout.
Zihni Onur Uygun
wiley   +1 more source

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