Results 31 to 40 of about 17,751,190 (266)

ZO-2 induces cytoplasmic retention of YAP by promoting a LATS1-ZO-2-YAP complex at tight junctions [PDF]

open access: yes, 2018
Summary Contact inhibition of proliferation (CIP) is a key mechanism that transduces the cell density status of tissue and organs into a unique transcriptional program by translocating YAP between the nucleus and the cytoplasm. However, the nature of the cell density-dependent cues that regulate the YAP distribution remains unclear ...
Liu, Olivia Xuan   +4 more
openaire   +1 more source

ZO-1- and ZO-2-Dependent Integration of Myosin-2 to Epithelial Zonula Adherens [PDF]

open access: yesMolecular Biology of the Cell, 2008
For the zonula adherens (ZA) to be established by linear arrangement of adherens junctions (AJs) in epithelial sheet cells, critical for the epithelial cell sheet formation and intercellular barrier function, myosin-2 is supposedly integrated into the ZA with the result of overlapping localization of E-cadherin/actin/myosin-2.
Yuji, Yamazaki   +6 more
openaire   +2 more sources

The antimicrobial effects of zinc oxide-calcium hydroxide mixture fillers: determining the ideal mixture ratio

open access: yesIranian Journal of Microbiology, 2019
Background and Objectives: Although zinc oxide (ZO)-calcium hydroxide (CaOH) mixtures have been successful regarding their absorption rate compatibility with dissolving primary teeth, no study has been conducted on the appropriate mixture ratio to obtain
Ali Nozari   +3 more
doaj   +1 more source

The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density [PDF]

open access: yes, 2003
Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to participate in the control of epithelial cell proliferation and differentiation.
Balda, MS   +5 more
core   +1 more source

Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis [PDF]

open access: yesGastroenterology, 2019
BACKGROUND & AIMS Tight junctions (TJs) establish tissue barriers that maintain osmotic homeostasis and, in the liver, isolate bile flow from the blood circulation. ZO-2/Tjp2 is a scaffold protein that tethers TJ transmembrane proteins to the actin cytoskeleton.
Xu, Jianliang   +9 more
openaire   +2 more sources

Altered Expression of ZO-1 and ZO-2 in Sertoli Cells and Loss of Blood-Testis Barrier Integrity in Testicular Carcinoma In Situ

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Carcinoma in situ (CIS) is the noninvasive precursor of most human testicular germ cell tumors. In normal seminiferous epithelium, specialized tight junctions between Sertoli cells constitute the major component of the blood-testis barrier. Sertoli cells
Cornelia Fink   +6 more
doaj   +1 more source

ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. [PDF]

open access: yesPLoS ONE, 2014
ZO-1, ZO-2 and ZO-3 are tight junction-associated scaffold proteins that bind to transmembrane proteins of tight junctions and the underlying cytoskeleton.
Shinsaku Tokuda   +2 more
doaj   +1 more source

Calcium Binding Protein S100A16 Expedites Proliferation, Invasion and Epithelial-Mesenchymal Transition Process in Gastric Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Gastric cancer (GC) is one of the most common malignant tumors of the digestive system, listed as the second cause of cancer-related deaths worldwide. S100 Calcium Binding Protein A16 (S100A16) is an acidic calcium-binding protein associated with several
Xiaoying You   +12 more
doaj   +1 more source

Regulation of Tight Junctions by Sex Hormones in Goat Mammary Epithelial Cells

open access: yesAnimals, 2022
The sex hormones of estrogen and progesterone (P4) play a vital role in mammary gland development and milk lactation in ruminants. The tight junction (TJ) between adjacent secretory epithelial cells is instrumental in establishing the mammary blood–milk ...
Hongmei Zhu   +7 more
doaj   +1 more source

27-Hydroxycholesterol induces expression of zonula occludens-1 in monocytic cells via multiple kinases pathways

open access: yesScientific Reports, 2022
Zonula occludens (ZO)-1, a tight-junction protein (TJP), is expressed in dendritic cells (DCs) but not in monocytes, and 27-hydroxycholesterol (27OHChol) drives the differentiation of monocytes into DCs.
Hyok-rae Cho   +5 more
doaj   +1 more source

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