Results 51 to 60 of about 67,145 (262)

New chemical evolution analytical solutions including environment effects

, 2015
In the last years, more and more interest has been devoted to analytical solutions, including inflow and outflow, to study the metallicity enrichment in galaxies.
Spitoni, E.
core   +1 more source

Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. [PDF]

, 2020
Polarized distribution of organelles and molecules inside a cell is vital for a range of cellular processes and its loss is frequently encountered in disease.
Choi, Julie, Ear, Jason, Ghassemian, Majid, Ghosh, Pradipta, Kufareva, Irina, Rajapakse, Navin, Saklecha, Anokhi   +6 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Fourier-Laplace transform of irreducible regular differential systems on the Riemann sphere

, 2004
We show that the Fourier-Laplace transform of an irreducible regular differential system on the Riemann sphere underlies, when one only considers the part at finite distance, a polarizable regular twistor $\mathcal{D}$-module.
Sabbah, Claude
core   +5 more sources

Stability of Underwater Periodic Locomotion [PDF]

, 2013
Most aquatic vertebrates swim by lateral flapping of their bodies and caudal fins. While much effort has been devoted to understanding the flapping kinematics and its influence on the swimming efficiency, little is known about the stability (or lack of ...
Jing, Fangxu, Kanso, Eva
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Lipopolysaccharide downregulates the expression of ZO-1 protein through the Akt pathway

BMC Infectious Diseases, 2022
Background Neonatal bacterial meningitis is a common neonatal disease with high morbidity, and can cause serious sequelae when left untreated. Escherichia coli is the common pathogen, and its endotoxin, lipopolysaccharide (LPS) can damage the endothelial
Peicen Zou, Fan Yang, Yijun Ding, Di Zhang, Ying Liu, Jinjing Zhang, Dan Wu, Yajuan Wang   +7 more
doaj   +1 more source

Molecular genetics of chicken egg quality [PDF]

, 2010
Faultless quality in eggs is important in all production steps, from chicken to packaging, transportation, storage, and finally to the consumer. The egg industry (specifically transportation and packing) is interested in robustness, the consumer in ...
Honkatukia, Mervi
core   +1 more source

Solving the Topological String on K3 Fibrations

, 2009
We present solutions of the holomorphic anomaly equations for compact two-parameter Calabi-Yau manifolds which are hypersurfaces in weighted projective space.
A Albano, A Klemm, A Klemm, Albrecht Klemm, B Haghighat, B Haghighat, Babak Haghighat, BR Greene, C Peskine, C Vafa, D Cox, D Gepner, D Zagier, E Witten, G Curio, I Antoniadis, I Antoniadis, I Antoniadis, I Antoniadis, IM Gel’fand, IM Gel’fand, K Oguiso, M Alim, M Bershadsky, M Bershadsky, M Mariño, M Mariño, M-X Huang, M-X Huang, N Seiberg, P Candelas, P Griffiths, PS Aspinwall, R Borcherds, S Ferrara, S Hosono, S Hosono, S Kachru, S Kachru, S Yamaguchi, SH Katz, SH Katz, T Kawai, TW Grimm, TW Grimm, V Bouchard, VV Batyrev, W Fulton   +47 more
core   +2 more sources

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source