Results 31 to 40 of about 8,610 (178)

Scutellarin‑treated exosomes increase claudin 5, occludin and ZO1 expression in rat brain microvascular endothelial cells

Experimental and Therapeutic Medicine, 2019
Homocysteine has been reported to be an independent risk factor for stroke. Scutellarin (Scu) dilates cerebral blood vessels and promotes anti-platelet aggregation; however, the mechanism by which Scu and Scu-treated exosomes protect against cerebrovascular disease is unclear.
Zhong, Xiaoqin, Luo, Chuanjin, Deng, Minzhen, Zhao, Min   +3 more
openaire   +3 more sources

ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape. [PDF]

PLoS ONE, 2014
ZO-1, ZO-2 and ZO-3 are tight junction-associated scaffold proteins that bind to transmembrane proteins of tight junctions and the underlying cytoskeleton.
Shinsaku Tokuda, Tomohito Higashi, Mikio Furuse   +2 more
doaj   +1 more source

Establishment of a novel probe-based RT-qPCR approach for detection and quantification of tight junctions reveals age-related changes in the gut barriers of broiler chickens.

PLoS ONE, 2021
Tight junctions (TJs) play a dominant role in gut barrier formation, therefore, resolving the structures of TJs in any animal species is crucial but of major importance in fast growing broilers. They are regulated in molecular composition, ultrastructure
J Sophia von Buchholz, Ivana Bilic, Jörg R Aschenbach, Michael Hess, Taniya Mitra, Wageha A Awad   +5 more
doaj   +1 more source

Effects of multi-strain probiotic supplementation on intestinal microbiota, tight junctions, and inflammation in young broiler chickens challenged with subsp. [PDF]

Asian-Australasian Journal of Animal Sciences, 2020
Objective This study assessed the effects of probiotics on cecal microbiota, gene expression of intestinal tight junction proteins, and immune response in the cecal tonsil of broiler chickens challenged with Salmonella enterica subsp. enterica.
Chi Huan Chang, Po Yun Teng, Tzu Tai Lee, Bi Yu   +3 more
doaj   +1 more source

Assembly of an SAP97-AKAP79-cAMP-dependent Protein Kinase Scaffold at the Type 1 PSD-95/DLG/ZO1 Motif of the Human β1-Adrenergic Receptor Generates a Receptosome Involved in Receptor Recycling and Networking [PDF]

Journal of Biological Chemistry, 2007
Appropriate trafficking of the beta(1)-adrenergic receptor (beta(1)-AR) after agonist-promoted internalization is crucial for the resensitization of its signaling pathway. Efficient recycling of the beta(1)-AR required the binding of the protein kinase A anchoring protein-79 (AKAP79) to the carboxyl terminus of the beta(1)-AR (Gardner, L.
Lidia A, Gardner, Anjaparavanda P, Naren, Suleiman W, Bahouth   +2 more
openaire   +2 more sources

sox10 mutants have altered intestinal tight junctions.

, 2022
(A) Quantification of percent ZO1 colocalized with Occludin in the “ileum-like” region of CV and GF larvae. (B) Representative immunohistochemistry of CV WT and sox10 mutant ZO1, Occludin and colocalization in “ileum-like” region.
Elena S. Wall (5436347), Catherine D. Robinson (6066086), M. Kristina Hamilton (9162785), Karen Guillemin (46245), Judith S. Eisen (12072005)   +4 more
core   +1 more source

[HBx promotes ubiquitination and degradation of ZO1 and increases the migration and invasion of liver cancer cells].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2022
Objective: To study the effect of hepatitis B virus X protein (HBx) expression level on migration and invasion of zonula occludens protein-1 (ZO-1) in HepG2 liver cancer cells. Methods: Liver cancer cells were transfected with HBV full gene plasmid (pcDNA3.1-HBV1.
S J, Yang, L S, Jiang, Q, Hu, C, Xie, X, Zhan, W X, Chen   +5 more
openaire   +3 more sources

Protein Nanoparticle-Related Osmotic Pressure Modifies Nonselective Permeability of the Blood–Brain Barrier by Increasing Membrane Fluidity

International Journal of Nanomedicine, 2021
Chen Li,1,2,* LinLin Chen,1,2,* YuanYuan Wang,1,2 TingTing Wang,1,2 Dong Di,1,2 Hao Zhang,1,3 HuanHuan Zhao,1,2 Xu Shen,1,2 Jun Guo1– 3 1School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing ...
Li C, Chen L, Wang Y, Wang T, Di D, Zhang H, Zhao H, Shen X, Guo J   +8 more
doaj  

E12.5 mouse dorsal cortex, mInsc OE, EGFP-ZO1, mem-CyRFP

, 2019
Additional time-lapse movies for Figure 5l,m. E12.5 mouse dorsal cortex, mInsc OE, DMSO control, EGFP-ZO1, mem-CyRFP.
Atsunori Shitamukai (7859580), Fumio Matsuzaki (131236)   +1 more
core   +1 more source

Examination of the Potential for ZO1 and ZEB2 to Mediate the Effects of AJAP1 in Epithelial Cells During Cardiovascular Development

, 2022
Formation of the epicardium by epithelial cells is impaired in Tbx5-deficient mouse hearts. These embryonic mice have reduced cardiac Ajap1 mRNA expression.
Gerick, Alexander
core