Results 111 to 120 of about 31,557 (233)

Inhibition of MicroRNA‐155 Supports Endothelial Tight Junction Integrity Following Oxygen‐Glucose Deprivation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ...
Juan Carlos Pena‐Philippides, Amy Sabrina Gardiner, Ernesto Caballero‐Garrido, Rong Pan, Yiliang Zhu, Tamara Roitbak   +5 more
doaj   +1 more source

Molecular And Immunological Characteristics Of Vibrio Cholerae And Vibrio Alginolyticus [PDF]

, 2000
Twenty isolates of Vibrio cholerae and four isolates of Vibrio alginolyticus used in this study were identified using the conventional biochemical tests.
Neela, Vasanthakumari
core  

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

Mechanisms regulating intestinal barrier integrity and its pathological implications [PDF]

, 2018
The gastrointestinal tract is a specialized organ in which dynamic interactions between host cells and the complex environment occur in addition to food digestion.
CHAITHANYA, LAKSHMI CHELAKKOT GOVINDALAYA, Ghim, Jaewang, Ryu, Sung Ho   +2 more
core   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Diversity in protein–protein interactions of connexins: emerging roles [PDF]

, 2004
Gap junctions, specialised membrane structures that mediate cell-to-cell communication in almost all tissues, are composed of channel-forming integral membrane proteins termed connexins.
Duffy, Thomas, Levitan, Aasland, Harris, White, Bruzzone, Kwak, Ahmad, Liu, Morley, Homma, Zhou, Revilla, Peracchia, Moreno, Duffy, Hoshi, Stergiopoulos, Anumonwo, Songyang, Nourry, Fanning, Saimi, Peracchia, Van Eldik, Török, Sotkis, Gonzalez-Mariscal, Kausalya, Laing, Guerrier, Barker, Barker, Toyofuku, Wu, Day, Kojima, Defamie, Giepmans, Luque, Toyofuku, Doyle, Toyofuku, Laing, Kojima, Kojima, Nielsen, Nielsen, Nielsen, Nagaoka, Nusrat, Ai, Xu, Fujimoto, Nagafuchi, Singh, Gutstein, Meyer, Kostin, Jongen, Hernandez-Blazquez, Swenson, Loo, Warn-Cramer, Kanemitsu, Giepmans, Doble, Bowling, Schulz, Cooper, Mussini, Schiavon, Cooper, Giepmans, Giepmans, Murray, Thomas, Lo, Yamane, Butkevich, Schubert, Naus, Huang, Ciechanover, Pickart, Hicke, Laing, Hülser, Rutz, Jin, Jin, Thalmann, Wang, Gupta, McLeod, Rodina, Kay, Calero, TenBroek, Martin, Mitic, Fishman, Dunham, Martin, Lauf, Johnson, Govindarajan, Johnson, Frenzel, Hertig, Anderson, Laing, Thomas, Goldberg, Guan, Guo, Beardslee, Woodward, Prowse, Wang, Hsu, Verrecchia, Noma, Cruciani, TenBroek, Hossain, Hossain, Duthe, van Veen, Traub, Kwak, Li, Shiokawa-Sawada, Warn-Cramer, Bukauskas, Jugloff, Koval, Goldberg, Theiss, Yamane, Cotrina, Cotrina, Plotkin, Duffy, Itoh, Mitic, Sheng, Davis, Giepmans   +149 more
core   +1 more source

Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse

Developmental Biology, 2008
It is unknown whether or not tight junction formation plays any role in morula to blastocyst transformation that is associated with development of polarized trophoblast cells and fluid accumulation. Tight junctions are a hallmark of polarized epithelial cells and zonula occludens-1 (ZO-1) is a known key regulator of tight junction formation.
Wang, Hehai, Ding, Tianbing, Brown, Naoko, Yamamoto, Yasutoshi, Prince, Lawrence S., Reese, Jeff, Paria, B.C.   +6 more
openaire   +2 more sources

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

AIDS Research and Therapy, 2009
Background HIV-infected individuals are at increased risk for acute and chronic airway disease even though there is no evidence that the virus can infect the lung epithelium.
Jacob Barbara A, Joshi Pratibha C, Fan Xian, Lassiter Coy, Sutliff Roy L, Jones Dean P, Koval Michael, Guidot David M   +7 more
doaj   +1 more source

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. [PDF]

, 2012
International audienceABSTRACT: The Blood--brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and ...
Artus, Cédric, Couraud, Pierre-Olivier, Ganeshamoorthy, Kayathiri, Glacial, Fabienne, Luissint, Anny-Claude   +4 more
core   +4 more sources