27-Hydroxycholesterol induces expression of zonula occludens-1 in monocytic cells via multiple kinases pathways [PDF]
Zonula occludens (ZO)-1, a tight-junction protein (TJP), is expressed in dendritic cells (DCs) but not in monocytes, and 27-hydroxycholesterol (27OHChol) drives the differentiation of monocytes into DCs.
Hyok-rae Cho +5 more
doaj +5 more sources
Serum Zonula Occludens-1 and Claudin-5 Levels in Patients with Insomnia Disorder: A Pilot Study [PDF]
Mei Fan, Fangyi Deng, Rui Tang, Yixian Cai, Xiaotao Zhang, Hongyao Li, Ting Xiang, Jiyang Pan Department of Psychiatry, Sleep Medicine Centre, The First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of ChinaCorrespondence: Jiyang ...
Fan M +7 more
doaj +4 more sources
Arecoline induces TNF-alpha production and Zonula Occludens-1 redistribution in mouse Sertoli TM4 cells. [PDF]
BackgroundArecoline, a major alkaloid in Areca nut has the ability to induce oxidative stress. The effect of Areca nut, arecoline on reducing sperm quality and quantity were documented previously using several animal models.
Kuo TM +7 more
europepmc +5 more sources
RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer. [PDF]
Background:The transforming growth factor-β (TGF-β) pathway plays a vital role in driving cancer cell epithelial–mesenchymal transition (EMT). Zonula occludens-1 (ZO-1), which is downregulated in response to TGF-β, is able to control endothelial cell ...
Wu J +9 more
europepmc +2 more sources
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1. [PDF]
Zinc finger protein 668 (ZNF668) is a recently discovered protein and its expression levels, as well as its involvement in the invasion and metastasis of non-small cell lung cancer (NSCLC), are largely unknown.
Zhang X +7 more
europepmc +2 more sources
Ankrd1-mediated signaling is supported by its interaction with zonula occludens-1 [PDF]
The muscle ankyrin repeat protein Ankrd1 is localized in a mechanosensory complex of the sarcomeric I-band. It is involved in signaling pathways activated in response to mechanical stretch.
Nestorović Aleksandra +4 more
doaj +3 more sources
Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes. [PDF]
Purpose The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine whether montelukast, a ...
Park SJ +4 more
europepmc +2 more sources
Rhubarb attenuates blood-brain barrier disruption via increased zonula occludens-1 expression in a rat model of intracerebral hemorrhage. [PDF]
Blood-brain barrier (BBB) disruption is a key pathophysiological factor of intracerebral hemorrhage (ICH). The level of zonula occludens-1 (ZO-1) has been closely associated with the degree of BBB damage, and is an indicator of BBB destruction.
Wang Y +6 more
europepmc +2 more sources
Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation [PDF]
Rickettsia spp. cause life-threatening diseases in humans. The fundamental pathophysiological changes in fatal rickettsial diseases are disrupted endothelial barrier and increased microvascular permeability.
Loka Reddy Velatooru +8 more
doaj +2 more sources
Glomerular changes and alterations of zonula occludens-1 in the kidneys of Plasmodium falciparum malaria patients. [PDF]
BackgroundThe process of cytoadhesion in Plasmodium falciparum malaria infection causes signaling processes that lead to structural and functional changes at the cellular level. Histopathological changes of acute kidney injury (AKI) in P.
Wichapoon B +3 more
europepmc +2 more sources

