Ankrd1-mediated signaling is supported by its interaction with zonula occludens-1 [PDF]
Archives of Biological Sciences, 2014 The muscle ankyrin repeat protein Ankrd1 is localized in a mechanosensory complex of the sarcomeric I-band. It is involved in signaling pathways activated in response to mechanical stretch.
Nestorović Aleksandra +4 more
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Tight junctions expression is affected by active, inactive, and derivatives of Akkermansia muciniphila [PDF]
Iranian Journal of MicrobiologyBackground and Objectives: Tight junctions (TJs) in the gastrointestinal tract are comprised of various junctional proteins including Occludin and Zonula Occludens (ZO-1) that have a critical role in epithelial barrier function. Gut microbiota and their
Farinaz Ghaderi +6 more
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Zonula occludens 1 as a novel biomarker in decompensated alcoholic cirrhosis with hepatorenal syndrome [PDF]
Exploration of Digestive DiseasesAim: Our previous study provided evidence that systemic zonula occludens (ZO) 1 levels are elevated in cirrhotic and hepatocellular carcinoma (HCC) patients. Here, we aimed to evaluate serum ZO-1 levels in patients with decompensated alcoholic cirrhosis (
Balasubramaniyan Vairappan +2 more
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Neuroprotective effects of ulinastatin on Escherichia coli meningitis rats through inhibiting PKCα phosphorylation and reducing zonula occludens-1 degradation [PDF]
Scientific ReportsUlinastatin, a broad-spectrum inflammatory inhibitor widely employed in the management of severe pancreatitis and sepsis, has not been extensively investigated for its therapeutic potential in bacterial meningitis.
Xiaolan Zheng +9 more
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Immunohistochemical Analysis of Vimentin and Zonula Occludens-1 in Placentas of Patients with PPROM
Clinical and Experimental Obstetrics & GynecologyBackground: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM).
Fuat Zaman +5 more
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Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression. [PDF]
PLoS ONE, 2012 Normal airway epithelial barrier function is maintained by cell-cell contacts which require the translocation of adhesion proteins at the cell surface, through membrane vesicle trafficking and fusion events.
Cleo Leung +3 more
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Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis
Veterinary Sciences and Practices, 2023 İlknur ÜNDAĞ +1 more
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Zonula occludens-1 distribution and barrier functions are affected by epithelial proliferation and turnover rates. [PDF]
Cell Prolif, 2023 AbstractZonula occludens‐1 (ZO‐1) is a scaffolding protein of tight junctions, which seal adjacent epithelial cells, that is also expressed in adherens junctions. The distribution pattern of ZO‐1 differs among stratified squamous epithelia, including that between skin and oral buccal mucosa.
Imafuku K +8 more
europepmc +3 more sources
Hypertonic Stress Promotes the Upregulation and Phosphorylation of Zonula Occludens 1 [PDF]
Nephron Physiology, 2011 Tight junction molecules form a barrier between adjacent cells and mediate the cells’ ability to develop membranes that constitute boundaries of different compartments within the body. Membranes with selective ion and water passage are important for the electrolyte and water homeostasis in the kidney.
Cornelia, Then +5 more
openaire +4 more sources
Loss of Zonula Occludens-1 (ZO-1) Enhances Angiogenic Signaling in Ovarian Cancer Cells. [PDF]
Int J Mol SciZonula occludens-1 (ZO-1), encoded by the TJP1 gene, is a crucial scaffolding protein within tight junctions that maintains epithelial and endothelial barrier integrity. In addition to its structural role, ZO-1 participates in signal transduction pathways that influence various cellular processes such as proliferation, differentiation, and apoptosis ...
Choi S +9 more
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