Results 21 to 30 of about 36,822 (224)

PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65. [PDF]

Sci Rep, 2015
Atypical Protein Kinase C zeta (PKCζ) forms Partitioning-defective (PAR) polarity complex for apico-basal distribution of membrane proteins essential to maintain normal cellular junctional complexes and tissue homeostasis. Consistently, tumor suppressive
Paul A, Danley M, Saha B, Tawfik O, Paul S.   +4 more
europepmc   +2 more sources

Tight junctions expression is affected by active, inactive, and derivatives of Akkermansia muciniphila [PDF]

Iranian Journal of Microbiology
Background and Objectives: Tight junctions (TJs) in the gastrointestinal tract are comprised of various junctional proteins including Occludin and Zonula Occludens (ZO-1) that have a critical role in epithelial barrier function. Gut microbiota and their
Farinaz Ghaderi, Zahra Hajebrahimi, Abolfazl Fateh, Fattah Sotoodehnejadnematalahi, Sara Ahmadi Badi, Somayeh Vaezijoze, Seyed Davar Siadat   +6 more
doaj   +2 more sources

Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome

Journal of the Formosan Medical Association, 2014
Unique barrier properties of the urothelial surface membrane permit urine storage without contents leak into the bloodstream. Previous reports suggested that the bladder urothelial barrier might be compromised in interstitial cystitis/painful bladder ...
Jane-Dar Lee, Ming-Huei Lee
doaj   +2 more sources

Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia

Molecular Biology of the Cell, 2012
ETOC: Our study reveals that ZO proteins in fully polarized cells regulate the assembly and contractility of the perijunctional actomyosin ring associated with the adherens junction.
A. Fanning, C. V. Van Itallie, James M. Anderson   +2 more
semanticscholar   +3 more sources

Zonula occludens 1 as a novel biomarker in decompensated alcoholic cirrhosis with hepatorenal syndrome [PDF]

Exploration of Digestive Diseases
Aim: Our previous study provided evidence that systemic zonula occludens (ZO) 1 levels are elevated in cirrhotic and hepatocellular carcinoma (HCC) patients. Here, we aimed to evaluate serum ZO-1 levels in patients with decompensated alcoholic cirrhosis (
Balasubramaniyan Vairappan, Raj Kumar, Mukta Wyawahare   +2 more
doaj   +2 more sources

Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression. [PDF]

PLoS ONE, 2012
Normal airway epithelial barrier function is maintained by cell-cell contacts which require the translocation of adhesion proteins at the cell surface, through membrane vesicle trafficking and fusion events.
Cleo Leung, Furquan Shaheen, Pascal Bernatchez, Tillie-Louise Hackett   +3 more
doaj   +2 more sources

Toll-Like Receptor 4 Reduces Occludin and Zonula Occludens 1 to Increase Retinal Permeability Both in vitro and in vivo. [PDF]

J Vasc Res, 2017
Liu L, Jiang Y, Steinle JJ.
europepmc   +2 more sources

Neuroprotective effects of ulinastatin on Escherichia coli meningitis rats through inhibiting PKCα phosphorylation and reducing zonula occludens-1 degradation [PDF]

Scientific Reports
Ulinastatin, a broad-spectrum inflammatory inhibitor widely employed in the management of severe pancreatitis and sepsis, has not been extensively investigated for its therapeutic potential in bacterial meningitis.
Xiaolan Zheng, Junsheng Wang, Huihong Su, Lingling Wu, Yan Zhang, Qianqian Tang, Tingting Ban, Kun Xie, Chunmiao Wei, Caimei Lin   +9 more
doaj   +2 more sources

Connexin43 and zonula occludens-1 are targets of Akt in cardiomyocytes that correlate with cardiac contractile dysfunction in Akt deficient hearts. [PDF]

Biochim Biophys Acta Mol Basis Dis, 2018
Ock S, Lee WS, Kim HM, Park KS, Kim YK, Kook H, Park WJ, Lee TJ, Abel ED, Kim J.   +9 more
europepmc   +2 more sources

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

Molecular Biology of the Cell, 2011
Cx43 gap junctions (GJs) are integral to the function of the mammalian heart. It is shown that ZO-1 dynamically regulates the transition between Cx43 connexons and GJ intercellular channels, determining the balance of connexon-mediated cell permeability ...
J. M. Rhett, J. Jourdan, R. Gourdie
semanticscholar   +4 more sources