Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology. [PDF]
Obert E +6 more
europepmc +2 more sources
Immunohistochemical Analysis of Vimentin and Zonula Occludens-1 in Placentas of Patients with PPROM
Background: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM).
Fuat Zaman +5 more
doaj +3 more sources
Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis
İlknur ÜNDAĞ +1 more
doaj +2 more sources
Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome. [PDF]
Mellas RE +4 more
europepmc +2 more sources
Hypertonic Stress Promotes the Upregulation and Phosphorylation of Zonula Occludens 1 [PDF]
Tight junction molecules form a barrier between adjacent cells and mediate the cells’ ability to develop membranes that constitute boundaries of different compartments within the body. Membranes with selective ion and water passage are important for the electrolyte and water homeostasis in the kidney.
Cornelia, Then +5 more
openaire +4 more sources
Loss of Zonula Occludens-1 (ZO-1) Enhances Angiogenic Signaling in Ovarian Cancer Cells. [PDF]
Zonula occludens-1 (ZO-1), encoded by the TJP1 gene, is a crucial scaffolding protein within tight junctions that maintains epithelial and endothelial barrier integrity. In addition to its structural role, ZO-1 participates in signal transduction pathways that influence various cellular processes such as proliferation, differentiation, and apoptosis ...
Choi S +9 more
europepmc +3 more sources
IntroductionFermented egg-milk peptides (FEMPs) could enhance the colon-intestinal barrier and upgrade the expression of zonula occludens-1 and mucin 2.
Siwen Lyu +9 more
doaj +1 more source
Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage [PDF]
Aminosalicylates, corticosteroids and immunosuppressants are currently the therapeutic choices in inflammatory bowel diseases (IBD), however, with limited remission and often serious side effects.
Brun, Paola +10 more
core +11 more sources
With the recent advances in medicine, human life expectancy is increasing; however, the extra years of life are not necessarily spent in good health or free from disability, resulting in a significantly higher incidence of age-associated pathologies ...
Jacopo Junio Valerio Branca +8 more
doaj +1 more source
Telmisartan increases the permeability of endothelial cells through zonula occludens-1.
Angiotensin receptor-1 blockers (ARBs) have been used for the treatment of atherosclerosis. Tight junctions are very important in the regulation of cellular permeability which may have a profound role in atherosclerosis. The relationship between them is unresolved.
C. Bian, Yihua Wu, Pengxu Chen
semanticscholar +4 more sources

