Results 51 to 60 of about 36,822 (224)

Effects of dietary Clostridium butyricum on the growth performance and intestinal health of hybrid groupers (Epinephelus lanceolatus♂ × E. fuscoguttatus♀)

open access: yesAquaculture Reports, 2023
s: This trial was performed to investigate the effects of Clostridium butyricum on growth and intestinal health of hybrid groupers (Epinephelus lanceolatus♂ × E. fuscoguttatus♀). 300 hybrid groupers were fed five diets containing C.
Keng Yang   +7 more
doaj   +1 more source

Effects of acute and chronic disease on cell junctions in mouse liver

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout   +2 more
doaj   +1 more source

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription [PDF]

open access: yes, 2009
Epithelial tight junctions recruit different types of signalling proteins that regulate cell proliferation and differentiation. Little is known about how such proteins interact functionally and biochemically with each other.
Aijaz, S.   +4 more
core   +2 more sources

Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia‐Reperfusion Injury

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background α Carboxyl terminus 1 (αCT1) is a 25–amino acid therapeutic peptide incorporating the zonula occludens‐1 (ZO‐1)–binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on chronic wounds.
Jingbo Jiang   +12 more
doaj   +1 more source

Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

open access: yesAntioxidants, 2021
Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process.
Adriana Cortés   +8 more
doaj   +1 more source

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]

open access: yes, 2016
Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core   +1 more source

Zonula occludens‐1 and connexin 43 expression in the failing human heart [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2007
AbstractFocal disorganization of gap junctional distribution and down‐regulation of the major gap junctional protein connexin 43 are typical features of myocardial remodelling in the failing human heart. Increasing evidence indicates that connexin 43 interacts with zonula‐occludens‐1 (ZO‐1), and it has recently been shown that ZO‐1 promotes the ...
openaire   +2 more sources

En face optical coherence tomography of foveal microstructure in full-thickness macular hole: a model to study perifoveal müller cells. [PDF]

open access: yes, 2015
PURPOSE: To characterize perifoveal intraretinal cavities observed around full-thickness macular holes (MH) using en face optical coherence tomography and to establish correlations with histology of human and primate maculae.
Behar-Cohen, F.   +7 more
core   +1 more source

Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption [PDF]

open access: yes, 2020
The epithelial sodium channel (ENaC) can increase the colonic absorptive capacity for salt and water. Campylobacter concisus is a common pathogenic epsilonproteobacterium, causing enteritis and diarrhea. It can induce barrier dysfunction in the intestine,
Bereswill, Stefan   +15 more
core   +2 more sources

Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni [PDF]

open access: yes, 2019
Campylobacter jejuni (C. jejuni) is the most common cause of foodborne gastroenteritis worldwide. The bacteria induce diarrhea and inflammation by invading the intestinal epithelium. Curcumin is a natural polyphenol from turmeric rhizome of Curcuma longa,
Bereswill, Stefan   +14 more
core   +1 more source

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