Results 11 to 20 of about 29,405 (257)

Chronic hypoxia down-regulates tight junction protein ZO-2 expression in children with cyanotic congenital heart defect [PDF]

, 2015
AIMS: Tight junction protein zonula occludens protein 2 (ZO-2) is a member of the membrane-associated guanylate kinases protein family known to be expressed at tight junctions of epithelial and endothelial cells and at adherens junctions (AJs) in ...
Angelini, GD, Caputo, M, Ghorbel, MT, Jenkins, EL   +3 more
core   +3 more sources

Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. [PDF]

PLoS ONE, 2012
BACKGROUND: Venous leg ulcers can be very hard to heal and represent a significant medical need with no effective therapeutic treatment currently available.
Ariadna Mendoza-Naranjo, Peter Cormie, Antonio E Serrano, Rebecca Hu, Shay O'Neill, Chiuhui Mary Wang, Christopher Thrasivoulou, Kieran T Power, Alexis White, Thomas Serena, Anthony R J Phillips, David L Becker   +11 more
doaj   +1 more source

Expression of Tight Junction Proteins Is Altered in Bladder Cancer

Analytical Cellular Pathology, 2020
Bladder cancer (BC) is one of the tumors which occur most frequently in urological system, but less is known about the expression of tight junction proteins and its clinical significance in BC.
Bangbin Chen, Renge Bu, Xuewen Xu
doaj   +1 more source

DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier InjurySummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Tumor necrosis factor (TNF) superfamily member tumor necrosis factor–like protein 1A (TL1A) has been associated with the susceptibility and severity of inflammatory bowel diseases. However, the function of the tumor necrosis factor–
Yosuke Shimodaira, Shyam K. More, Hussein Hamade, Anna Y. Blackwood, Jay P. Abraham, Lisa S. Thomas, Jordan H. Miller, Dalton T. Stamps, Sofi L. Castanon, Noam Jacob, Connie W.Y. Ha, Suzanne Devkota, David Q. Shih, Stephan R. Targan, Kathrin S. Michelsen   +14 more
doaj   +1 more source

Effect of oral administration of Limosilactobacillus reuteri on intestinal barrier function and mucosal immunity of suckling piglets

Italian Journal of Animal Science, 2022
The aim of present study was to evaluate the effect of Limosilactobacillus reuteri (L. reuteri) on the intestinal barrier function and mucosal immunity of piglets at different suckling phase.
Qi Wang, Jing Wang, Renli Qi, Xiaoyu Qiu, Qian Sun, Jinxiu Huang, Ruisheng Wang   +6 more
doaj   +1 more source

Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome

Journal of Translational Medicine, 2023
Background Preclinical studies in acute respiratory distress syndrome (ARDS) have suggested that inhaled sevoflurane may have lung-protective effects and clinical trials are ongoing to assess its impact on major clinical outcomes in patients with ARDS ...
Ruoyang Zhai, Woodys Lenga Ma Bonda, Charlotte Leclaire, Cécile Saint-Béat, Camille Theilliere, Corinne Belville, Randy Coupet, Raiko Blondonnet, Damien Bouvier, Loic Blanchon, Vincent Sapin, Matthieu Jabaudon   +11 more
doaj   +1 more source

Localization and expression of zonula occludens-1 tight junction-associated protein in baboon (Papio anubis) corpora lutea [PDF]

Human Reproduction, 1996
The identification of the cell junction-forming proteins connexin-43, a gap junction protein and E-cadherin, which is a component of adherent junctions, in the corpus luteum of both humans and baboons suggests that cell-cell interactions and metabolic cooperation must occur in this tissue.
F S, Khan-Dawood, J, Yang, M Y, Dawood
openaire   +2 more sources

Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage [PDF]

, 2015
Aminosalicylates, corticosteroids and immunosuppressants are currently the therapeutic choices in inflammatory bowel diseases (IBD), however, with limited remission and often serious side effects.
Brun, Paola, Caparrotta, Laura, Carrara, Maria, Castagliuolo, Ignazio, Catanzaro, Daniela, Dall'Acqua, Stefano, Giron, Maria Cecilia, Montopoli, Monica, Orso, Genny, Ragazzi, Eugenio, Serena, Rancan   +10 more
core   +5 more sources

Loss and reappearance of gap junctions in regenerating liver [PDF]

, 1978
Changes in intercellular junctional morphology associated with rat liver regeneration were examined in a freeze-fracture study. After a two-thirds partial hepatectomy, both gap junctions and zonulae occludentes were drastically altered.
Revel, J.-P., Yee, A. G.
core   +2 more sources

Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia‐Reperfusion Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background α Carboxyl terminus 1 (αCT1) is a 25–amino acid therapeutic peptide incorporating the zonula occludens‐1 (ZO‐1)–binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on chronic wounds.
Jingbo Jiang, Daniel Hoagland, Joseph A. Palatinus, Huamei He, Jegan Iyyathurai, L. Jane Jourdan, Geert Bultynck, Zhen Wang, Zhiwei Zhang, Kevin Schey, Steven Poelzing, Francis X. McGowan, Robert G. Gourdie   +12 more
doaj   +1 more source