Neuronal connexin36 association with zonula occludens‐1 protein (ZO‐1) in mouse brain and interaction with the first PDZ domain of ZO‐1 [PDF]
AbstractAmong the 20 members in the connexin family of gap junction proteins, only connexin36 (Cx36) is firmly established to be expressed in neurons and to form electrical synapses at widely distributed interneuronal gap junctions in mammalian brain.
Xinbo, Li +6 more
openaire +2 more sources
Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2
Background: Tight junctions are required for epithelial barrier formation and participate in the regulation of signalling mechanisms that control proliferation and differentiation.
Aijaz Saima +7 more
core +1 more source
Dual Roles of Tight Junction-associated Protein, Zonula Occludens-1, in Sphingosine 1-Phosphate-mediated Endothelial Chemotaxis and Barrier Integrity [PDF]
In this report, sphingosine-1-phosphate (S1P), a serum-borne bioactive lipid, is shown to activate tight-junction-associated protein Zonula Occludens-1 (ZO-1), which in turn plays a critical role in regulating endothelial chemotaxis and barrier integrity.
Jen-Fu, Lee +7 more
openaire +2 more sources
Electrical synaptic transmission requires a postsynaptic scaffolding protein
Electrical synaptic transmission relies on neuronal gap junctions containing channels constructed by Connexins. While at chemical synapses neurotransmitter-gated ion channels are critically supported by scaffolding proteins, it is unknown if channels at ...
Abagael M Lasseigne +9 more
doaj +1 more source
The aim of this work was to evaluate the impacts of feeding different levels of postbiotic RI11 on antioxidant enzyme activity, physiological stress indicators, and cytokine and gut barrier gene expression in broilers under heat stress.
Ali Merzza Humam +6 more
doaj +1 more source
Progesterone is neuroprotective by inhibiting cerebral edema after ischemia
Ischemic edema can alter the structure and permeability of the blood-brain barrier. Recent studies have reported that progesterone reduces cerebral edema after cerebral ischemia.
Yuan-zheng Zhao +3 more
doaj +1 more source
Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin43 Indicates Signaling between Binding Domains for c-Src and Zonula Occludens-1 [PDF]
Regulation of cell-cell communication by the gap junction protein connexin43 can be modulated by a variety of connexin-associating proteins. In particular, c-Src can disrupt the connexin43 (Cx43)-zonula occludens-1 (ZO-1) interaction, leading to down-regulation of gap junction intercellular communication. The binding sites for ZO-1 and c-Src correspond
Paul L, Sorgen +5 more
openaire +2 more sources
Tight junction protein levels of occludin, claudin-1 and zonula occludens-1 (ZO-1).
(A) shows representative blots of occludin, claudin, zonula occludens-1 (ZO-1), and β-actin on 0, 3, 7 and 14 post-weaning, respectively. (B) shows relative tight junction proteins expression. Data are means ± SD.
Kan Xiao (623589) +4 more
core +1 more source
Hypertonic Stress Promotes the Upregulation and Phosphorylation of Zonula Occludens 1 [PDF]
Tight junction molecules form a barrier between adjacent cells and mediate the cells' ability to develop membranes that constitute boundaries of different compartments within the body.
Tobias Bergler +10 more
core +1 more source
Intestinal inflammation and bacterial infections challenges in the aquaculture of American bullfrogs (Aquarana catesbeiana), impacting their health and productivity.
Kesong Chen +11 more
doaj +1 more source

