Results 31 to 40 of about 21,719 (253)
Beneficial Effects of Quercetin on Microcystin-LR Induced Tight Junction Defects
Frontiers in Pharmacology, 2021 Quercetin has numerous functions including antioxidant and anti-inflammatory effects. The beneficial effect of quercetin against microcystin-LR (MC-LR)-induced testicular tight junctions (TJs) defects in vitro and in vivo were investigated.
Yuan Zhou +7 more
doaj +1 more source
Molecules, 2021 PDZ (postsynaptic density (PSD95), discs large (Dlg), and zonula occludens (ZO-1)-dependent interactions are widely distributed within different cell types and regulate a variety of cellular processes.
Luis H. Gutiérrez-González +5 more
doaj +1 more source
Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology [PDF]
Journal of Molecular Medicine, 2017 A critical target tissue in age-related macular degeneration (AMD) is the retinal pigment epithelium (RPE), which forms the outer blood-retina barrier (BRB). RPE-barrier dysfunction might result from attenuation/disruption of intercellular tight junctions. Zonula occludens-1 (ZO-1) is a major structural protein of intercellular junctions.
Elisabeth Obert +6 more
openaire +2 more sources
International Journal of Immunopathology and Pharmacology, 2020 Emodin is an effective component in rhubarb to cure intestinal dysfunction, but the specific mechanism remains unknown. This study aimed to evaluate the protective effects of emodin on intestinal dysfunction caused by acute severe pancreatitis and reveal
Yang Tan +6 more
doaj +1 more source
The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. [PDF]
Proceedings of the National Academy of Sciences, 1996 The junction-associated protein zonula occludens-1 (ZO-1) is a member of a family of membrane-associated guanylate kinase homologues thought to be important in signal transduction at sites of cell-cell contact. We present evidence that under certain conditions of cell growth, ZO-1 can be detected in the nucleus.
C J, Gottardi +3 more
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A proper protocol for isolation of retinal pigment epithelium from rabbit eyes
Advanced Biomedical Research, 2014 Background: Retinal pigment epithelium (RPE) is a hexagonal monolayer of pigmented cells located between the neural retina and the choroid with an essential role for visual function.
Noushin Amirpour +4 more
doaj +1 more source
Neoplasma, 2019 Cancer cell invasion is an important characteristic of malignant tumors. Cancer cells overcome the constraints of tight junctions (TJ) to invade other tissues, but less is known about the regulating role of tight junction on bladder cancer (BC) invasion.
X, Xu, K, You, B, Wu
openaire +3 more sources
Molekularbiologische und NMR-Spektroskopische Charakterisierung der Komplexbildung des Afadin 6 mit den kleinen GTPasen Rap1A und H-Ras, sowie mit dem Tight Junction Protein Zonula occludens 1 [PDF]
, 2016 Ein Schwerpunkt dieser Arbeit war die Aufklärung der Interaktionsprozesse zwischen der Ras-Assoziations-Domäne 1 des Afadin 6 Proteins und den kleinen GTPasen Rap1A und H-Ras mit NMR-spektroskopischen Methoden.
Andrasch, Malte
core +1 more source
Animal Nutrition, 2021 This experiment was conducted to evaluate the effects of different levels of tannic acid (TA) on growth performance, diarrhea rate, nutrient digestibility and intestinal health in weaned piglets.
Yanyan Song +13 more
doaj +1 more source
Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes [PDF]
, 2015 PURPOSE: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine whether montelukast, a ...
Ha, TS +9 more
core +3 more sources