Results 11 to 20 of about 21,719 (253)
Ankrd1-mediated signaling is supported by its interaction with zonula occludens-1 [PDF]
Archives of Biological Sciences, 2014 The muscle ankyrin repeat protein Ankrd1 is localized in a mechanosensory complex of the sarcomeric I-band. It is involved in signaling pathways activated in response to mechanical stretch.
Nestorović Aleksandra +4 more
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Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. [PDF]
PLoS ONE, 2012 BACKGROUND: Venous leg ulcers can be very hard to heal and represent a significant medical need with no effective therapeutic treatment currently available.
Ariadna Mendoza-Naranjo +11 more
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Zonula Occludens-1, Occludin, and E-cadherin Protein Expression in Biliary Tract Cancers
Pathology & Oncology Research, 2009 The incidence of cholangiocarcinomas originating from intrahepatic and extrahepatic bile ducts, as well as of gallbladder carcinoma is increasing worldwide. The malignant transformation of biliary epithelia involves profound alterations of proteins in the intercellular junctions, among others zonula occludens-1 (ZO-1), occludin, and E-cadherin.
Németh, Zsuzsanna +9 more
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Zonula occludens and nasal epithelial barrier integrity in allergic rhinitis [PDF]
PeerJ, 2020 Allergic rhinitis (AR) is a common disease affecting 400 million of the population worldwide. Nasal epithelial cells form a barrier against the invasion of environmental pathogens. These nasal epithelial cells are connected together by tight junction (TJ)
Che Othman Siti Sarah +3 more
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Scientific ReportsUlinastatin, a broad-spectrum inflammatory inhibitor widely employed in the management of severe pancreatitis and sepsis, has not been extensively investigated for its therapeutic potential in bacterial meningitis.
Xiaolan Zheng +9 more
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Charakterisierung der Struktur, Funktion und Wechselwirkungen der Tight Junction Proteine Occludin und Zonula Occludens 1 [PDF]
, 2009 Die tight junction schränken die Diffusion durch den parazellulären Raum in Epithel- und Endothelzellschichten für viele Moleküle stark ein. Dadurch behindern sie die Aufnahme von wasserlöslichen Medikamenten in das dahinterliegende Gewebe. Zwei Proteine, die am tight junction Aufbau mitwirken, sind Zonula Occludens Protein 1 (ZO-1) und Occludin.
Walter, Juliane Katharina
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The Carboxyl Terminus of Neph Family Members Binds to the PDZ Domain Protein Zonula Occludens-1 [PDF]
Journal of Biological Chemistry, 2003 The PSD95/Dlg/ZO-1 (PDZ) domain-containing protein zonula occludens-1 (ZO-1) selectively localizes to the cytoplasmic basis of the slit diaphragm, a specialized cell-cell contact in between glomerular podocytes necessary to prevent the loss of protein in the urine. However, the function of ZO-1 at the slit diaphragm has remained elusive.
Huber, Tobias B. +8 more
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Expression of Tight Junction Proteins Is Altered in Bladder Cancer
Analytical Cellular Pathology, 2020 Bladder cancer (BC) is one of the tumors which occur most frequently in urological system, but less is known about the expression of tight junction proteins and its clinical significance in BC.
Bangbin Chen, Renge Bu, Xuewen Xu
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Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Tumor necrosis factor (TNF) superfamily member tumor necrosis factor–like protein 1A (TL1A) has been associated with the susceptibility and severity of inflammatory bowel diseases. However, the function of the tumor necrosis factor–
Yosuke Shimodaira +14 more
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Italian Journal of Animal Science, 2022 The aim of present study was to evaluate the effect of Limosilactobacillus reuteri (L. reuteri) on the intestinal barrier function and mucosal immunity of piglets at different suckling phase.
Qi Wang +6 more
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