Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health
Food Science &Nutrition, Volume 14, Issue 2, February 2026.Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu +4 more
wiley +1 more source
Brain and BehaviorBackground The neurovascular unit (NVU) and neurovascular trophic coupling (NVTC) play a key regulatory role in brain injury caused by ischemic stroke.
Hongyang Chen +3 more
doaj +1 more source
Beyond cell-cell adhesion: Emerging roles of the tight junction scaffold ZO-2 [PDF]
, 2013 Gehwolf, R. +6 more
core +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity
Protein Science, Volume 35, Issue 2, February 2026.Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin +3 more
wiley +1 more source
Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice
Allergy, Volume 81, Issue 2, Page 498-512, February 2026.Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek +7 more
wiley +1 more source
Modulation of transendothelial permeability and expression of ATP-binding cassette transporters in cultured brain capillary endothelial cells by astrocytic factors and cell-culture conditions [PDF]
, 2018 Confluent cell monolayers of brain capillary endothelial cells (BCEC) are used widely as an in vitro cell culture model of the blood-brain barrier. The present study describes the influence of cell-culture conditions on tight junctions, filamentous-actin
Drewe, Jürgen +4 more
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Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease
European Journal of Neuroscience, Volume 63, Issue 3, February 2026.This review discusses our current understanding of the structure–function, expression and roles in neural circuits of the less studied glutamate delta 1 (GluD1) receptor. Converging data suggests many unique features of GluD1 including expression at both excitatory and inhibitory synapses and binding to D‐serine and GABA.
Diane Choi +3 more
wiley +1 more source
Análisis de los efectos teratogénicos del ácido valproico en el desarrollo del tubo neural del pez cebra y los efectos protectores de la vitamina C [PDF]
, 2017 [Resumen:] El ácido valproico (VPA) es el principal anticonvulsionante utilizado contra la epilepsia. Sin embargo, durante la gestación actúa como teratógeno en las etapas iniciales del embarazo, principalmente ocasionando malformaciones en el sistema
González Arias, Ana
core
Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging [PDF]
, 2018 Chen, Wei +8 more
core +2 more sources