Results 151 to 160 of about 31,558 (238)
Da Yuan Yin Regulates Gut Microbiota and Improves Intestinal Injury in Sepsis
Sepsis mouse model was induced by LPS to investigate the effect of Da Yuan Yin (DYY) in vivo. Hematoxylin–eosin staining showed that DYY could reduce intestinal injury caused by sepsis. In addition, DYY can also inhibit inflammation, apoptosis, and promote cell proliferation in sepsis, and promote the expression of tight junction proteins.
Li Wang +4 more
wiley +1 more source
Atractylodes macrocephala polysaccharides alleviate diabetic liver and kidney injury in HFD/STZ‐induced mice by improving gut microbiota composition, restoring intestinal barrier function, and partially correcting disturbed unsaturated fatty acid metabolism.
Jiali Wu +12 more
wiley +1 more source
Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging [PDF]
Chen, Wei +8 more
core +2 more sources
Crocin enhanced intestinal barrier integrity and alleviated colonic inflammation in DSS‐induced UC mice. Crocin promoted autophagy by targeting the AMPK/mTOR pathway. Crocin reshaped gut microbiota composition of UC mice. ABSTRACT Crocin has been widely recognized for its anti‐inflammatory and antioxidant properties.
Jiaoyang Xu +8 more
wiley +1 more source
Anisakis simplex products impair intestinal epithelial barrier function and occludin and zonula occludens-1 localisation in differentiated Caco-2 cells. [PDF]
Carballeda-Sangiao N +6 more
europepmc +1 more source
[Expression of Zonula Occludens-1 in Cerebral Cortex Following Traumatic Brain Injury].
To observe the time-course expression of zonula occludens-1 (ZO-1) in cerebral cortex after traumatic brain injury (TBI).The TBI model of mouse was established. The mice were divided in 1 h, 3 h, 6 h, 12 h, 24 h, 3 d, 7 d after TBI, sham and control groups.
Tao, Wang +5 more
openaire +1 more source
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun +7 more
wiley +1 more source
Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He +10 more
wiley +1 more source
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy +16 more
wiley +1 more source
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto +8 more
wiley +1 more source

