Ankrd1-mediated signaling is supported by its interaction with zonula occludens-1 [PDF]
The muscle ankyrin repeat protein Ankrd1 is localized in a mechanosensory complex of the sarcomeric I-band. It is involved in signaling pathways activated in response to mechanical stretch.
Nestorović Aleksandra +4 more
doaj +5 more sources
Immunohistochemical Analysis of Vimentin and Zonula Occludens-1 in Placentas of Patients with PPROM [PDF]
Background: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM).
Fuat Zaman +5 more
doaj +4 more sources
Expression of Zonula Occludens-1 and Claudin-1 Proteins in Japanese Quails Testis
İlknur ÜNDAĞ +1 more
doaj +3 more sources
Zonula occludens 1 as a novel biomarker in decompensated alcoholic cirrhosis with hepatorenal syndrome [PDF]
Aim: Our previous study provided evidence that systemic zonula occludens (ZO) 1 levels are elevated in cirrhotic and hepatocellular carcinoma (HCC) patients. Here, we aimed to evaluate serum ZO-1 levels in patients with decompensated alcoholic cirrhosis (
Balasubramaniyan Vairappan +2 more
doaj +4 more sources
Effects of interleukin-13 and montelukast on the expression of zonula occludens-1 in human podocytes. [PDF]
The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and to determine whether montelukast, a leukotriene receptor antagonist, has an effect on ZO-1 restoration in cultured human podocytes.Human podocytes ...
Park SJ +4 more
europepmc +8 more sources
Loss of Zonula Occludens-1 (ZO-1) Enhances Angiogenic Signaling in Ovarian Cancer Cells. [PDF]
Zonula occludens-1 (ZO-1), encoded by the TJP1 gene, is a crucial scaffolding protein within tight junctions that maintains epithelial and endothelial barrier integrity. In addition to its structural role, ZO-1 participates in signal transduction pathways that influence various cellular processes such as proliferation, differentiation, and apoptosis ...
Choi S +9 more
europepmc +5 more sources
Hypertonic Stress Promotes the Upregulation and Phosphorylation of Zonula Occludens 1 [PDF]
Tight junction molecules form a barrier between adjacent cells and mediate the cells’ ability to develop membranes that constitute boundaries of different compartments within the body. Membranes with selective ion and water passage are important for the electrolyte and water homeostasis in the kidney.
Cornelia, Then +5 more
core +6 more sources
TAZ interacts with zonula occludens‐1 and ‐2 proteins in a PDZ‐1 dependent manner [PDF]
MINT‐7994937: ZO‐2 (uniprotkb:Q95168) binds (MI:0407) to TAZ (uniprotkb:Q9EPK5) by pull down (MI:0096) MINT‐7994900, MINT‐7994835, MINT‐7994885: ZO‐1 (uniprotkb:Q07157) physically interacts (MI:0915) with TAZ (uniprotkb:Q9EPK5) by pull down (MI:0096) MINT‐7995020: ZO‐2 (uniprotkb:Q9UDY2) and TAZ (uniprotkb:Q9GZV5) colocalize (MI:0403) by fluorescence ...
Remue, Eline +6 more
openaire +3 more sources
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epithelia [PDF]
The structure and function of both adherens (AJ) and tight (TJ) junctions are dependent on the cortical actin cytoskeleton. The zonula occludens (ZO)-1 and -2 proteins have context-dependent interactions with both junction types and bind directly to F-actin and other cytoskeletal proteins, suggesting ZO-1 and -2 might regulate cytoskeletal activity at ...
Fanning, Alan S. +2 more
openaire +3 more sources
Aspirin and nonsteroidal anti-inflammatory agents are known to induce gastroduodenal complications such as ulcer, bleeding, and dyspepsia. In this study, we examined the prophylactic effect of rebamipide, an anti-ulcer agent with free-radical scavenging ...
Takahiro Suzuki +11 more
doaj +2 more sources

