Zonula Occludens-1, Occludin, and E-cadherin Protein Expression in Biliary Tract Cancers
Pathology & Oncology Research, 2009 The incidence of cholangiocarcinomas originating from intrahepatic and extrahepatic bile ducts, as well as of gallbladder carcinoma is increasing worldwide. The malignant transformation of biliary epithelia involves profound alterations of proteins in the intercellular junctions, among others zonula occludens-1 (ZO-1), occludin, and E-cadherin.
Németh, Zsuzsanna +9 more
openaire +4 more sources
Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. [PDF]
PLoS ONE, 2012 BACKGROUND: Venous leg ulcers can be very hard to heal and represent a significant medical need with no effective therapeutic treatment currently available.
Ariadna Mendoza-Naranjo +11 more
doaj +3 more sources
Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1
Molecular Biology of the Cell, 2011 Connexin 43 (Cx43) is a gap junction (GJ) protein widely expressed in mammalian tissues that mediates cell-to-cell coupling. Intercellular channels comprising GJ aggregates form from docking of paired connexons, with one each contributed by apposing cells.
Rhett, J. Matthew +2 more
openaire +4 more sources
Zonula occludens-1 distribution and barrier functions are affected by epithelial proliferation and turnover rates. [PDF]
Cell Prolif, 2023 AbstractZonula occludens‐1 (ZO‐1) is a scaffolding protein of tight junctions, which seal adjacent epithelial cells, that is also expressed in adherens junctions. The distribution pattern of ZO‐1 differs among stratified squamous epithelia, including that between skin and oral buccal mucosa.
Imafuku K +8 more
europepmc +3 more sources
Structural and biochemical characterization of Zonula-Occludens-1.
, 2010 Structural and biochemical characterization of Zonula-Occludens ...
Ming Fong. Lye (7967327)
core +6 more sources
Frontiers in Nutrition, 2022 IntroductionFermented egg-milk peptides (FEMPs) could enhance the colon-intestinal barrier and upgrade the expression of zonula occludens-1 and mucin 2.
Siwen Lyu +9 more
doaj +1 more source
Connexin45 Interacts with Zonula Occludens-1 and Connexin43 in Osteoblastic Cells [PDF]
Journal of Biological Chemistry, 2001 The relative expression of connexin43 and connexin45 modulates gap junctional communication and production of bone matrix proteins in osteoblastic cells. It is likely that changes in gap junction permeability are determined by the interaction between these two proteins.
J G, Laing +4 more
openaire +2 more sources
Cells, 2023 With the recent advances in medicine, human life expectancy is increasing; however, the extra years of life are not necessarily spent in good health or free from disability, resulting in a significantly higher incidence of age-associated pathologies ...
Jacopo Junio Valerio Branca +8 more
doaj +1 more source
Dietary ethylenediamine dihydroiodide improves intestinal health in Cherry Valley ducks
Poultry Science, 2023 : This study investigated the effect of ethylenediamine dihydroiodide (EDDI) on the growth performance, thyroid function, immune function, intestinal development, intestinal permeability, intestinal barrier functions and microbial characteristics of ...
Yueqin Xie +10 more
doaj +1 more source
Confocal imaging dataset to assess endothelial cell orientation during extreme glucose conditions
Scientific Data, 2022 Measurement(s) nucleus • F-actin • zonula occludens 1 Technology Type(s) confocal microscopy Factor Type(s) line width • medium glucose concentration Sample Characteristic - Organism Mus musculus Machine-accessible metadata file describing the reported ...
Ana María Porras Hernández +4 more
doaj +1 more source