Results 31 to 40 of about 29,714,162 (232)

Quantification of Zonula Occludens-1 mRNA expression in cultu-red bovine retinal endothelial cells, using SYBR green real-time PCR [PDF]

open access: yes, 2008
A simple and rapid real-time reverse transcription-PCR (RT-PCR) technique using SYBR green fluorescence was developed to quantify Zonula Occludens-1 (ZO-1) mRNA expression in histamine-treated cultured bovine retinal microvessel endothelial cells.
Koon, C.Y.   +6 more
core   +5 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

Expression of Tight Junction Proteins Is Altered in Bladder Cancer

open access: yesAnalytical Cellular Pathology, 2020
Bladder cancer (BC) is one of the tumors which occur most frequently in urological system, but less is known about the expression of tight junction proteins and its clinical significance in BC.
Bangbin Chen, Renge Bu, Xuewen Xu
doaj   +1 more source

Effect of Changes in Photoperiods on Melatonin Expression and Gut Health Parameters in Laying Ducks

open access: yesFrontiers in Microbiology, 2022
We investigated the effect of photoperiod on ileal morphology, barrier function, short-chain fatty acid (SCFA) contents, microbial flora, melatonin expression, and synthesis in laying ducks.
Yao-ming Cui   +7 more
doaj   +1 more source

Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia‐Reperfusion Injury

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background α Carboxyl terminus 1 (αCT1) is a 25–amino acid therapeutic peptide incorporating the zonula occludens‐1 (ZO‐1)–binding domain of connexin 43 (Cx43) that is currently in phase 3 clinical testing on chronic wounds.
Jingbo Jiang   +12 more
doaj   +1 more source

Effects of dietary Clostridium butyricum on the growth performance and intestinal health of hybrid groupers (Epinephelus lanceolatus♂ × E. fuscoguttatus♀)

open access: yesAquaculture Reports, 2023
s: This trial was performed to investigate the effects of Clostridium butyricum on growth and intestinal health of hybrid groupers (Epinephelus lanceolatus♂ × E. fuscoguttatus♀). 300 hybrid groupers were fed five diets containing C.
Keng Yang   +7 more
doaj   +1 more source

Glomerular changes and alterations of zonula occludens-1 in the kidneys of Plasmodium falciparum malaria patients. [PDF]

open access: yesMalar J, 2014
Le processus de cytoadhésion dans l'infection par le paludisme à Plasmodium falciparum provoque des processus de signalisation qui conduisent à des changements structurels et fonctionnels au niveau cellulaire. Les changements histopathologiques de la lésion rénale aiguë (ira) dans le paludisme à P.
Wichapoon B   +3 more
europepmc   +4 more sources

Zonula occludens‐1 and connexin 43 expression in the failing human heart [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2007
AbstractFocal disorganization of gap junctional distribution and down‐regulation of the major gap junctional protein connexin 43 are typical features of myocardial remodelling in the failing human heart. Increasing evidence indicates that connexin 43 interacts with zonula‐occludens‐1 (ZO‐1), and it has recently been shown that ZO‐1 promotes the ...
openaire   +2 more sources

Lens Connexins α3Cx46 and α8Cx50 Interact with Zonula Occludens Protein-1 (ZO-1) [PDF]

open access: yesMolecular Biology of the Cell, 2003
Connexin α1Cx43 has previously been shown to bind to the PDZ domain–containing protein ZO-1. The similarity of the carboxyl termini of this connexin and the lens fiber connexins α3Cx46 and α8Cx50 suggested that these connexins may also interact with ZO-1. ZO-1 was shown to be highly expressed in mouse lenses.
Nielsen, Peter A   +6 more
openaire   +3 more sources

Effects of acute and chronic disease on cell junctions in mouse liver

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Cell junctions, including anchoring, occluding and communicating junctions, play an indispensable role in tissue architecture and homeostasis. Consequently, malfunctioning of cell junctions is linked with a wide range of disorders, including in liver ...
Raf Van Campenhout   +2 more
doaj   +1 more source

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