Results 81 to 90 of about 31,558 (238)
AnimalsTo investigate the effects of low net-energy (NE) diets on intestinal health in Tunchang pigs, 96 animals (25.40 ± 1.11 kg) were randomly assigned to four dietary treatment groups with NE levels of 9.82 (CG), 9.57 (EY1), 9.32 (EY2), and 9.07 (EY3) MJ/kg.
Xilong Yu +7 more
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ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer
Frontiers in Cell and Developmental Biology, 2021 Delocalization of zonula occludens-1 (ZO-1) from tight junctions plays a substantial role in epithelial cell plasticity observed during tumor progression. In vitro, we reported an impact of ZO-1 cyto-nuclear content in modulating the secretion of several
Déborah Neyrinck-Leglantier +13 more
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Advanced Science, EarlyView.A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Tumor necrosis factor (TNF) superfamily member tumor necrosis factor–like protein 1A (TL1A) has been associated with the susceptibility and severity of inflammatory bowel diseases. However, the function of the tumor necrosis factor–
Yosuke Shimodaira +14 more
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Regulation of CXCL8/IL-8 Expression by Zonula Occludens-1 in Human Breast Cancer Cells [PDF]
Molecular Cancer Research, 2012 Abstract Accumulating data now suggest that ZO-1, once delocalized from tight junctions, could be implicated in the regulation of tumor-promoting genes. Because of their major implication in different steps of tumor progression, we investigated here the influence of ZO-1 on chemokines expression in breast cancer cells.
Brysse, Anne +8 more
openaire +3 more sources
Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity
Advanced NanoBiomed Research, EarlyView.Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu +4 more
wiley +1 more source
Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer [PDF]
, 2016 Oral mucositis is one of the most common and debilitating side effects of chemotherapy treatment. Patients are often unable to eat and drink, which can lead to poor clinical outcomes and extensive resource utilisation.
Bowen, J. +4 more
core +1 more source
Animal Research and One Health, EarlyView.Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
Italian Journal of Animal Science, 2022 The aim of present study was to evaluate the effect of Limosilactobacillus reuteri (L. reuteri) on the intestinal barrier function and mucosal immunity of piglets at different suckling phase.
Qi Wang +6 more
doaj +1 more source
Tumour necrosis factor‐α‐induced loss of intestinal barrier function requires TNFR1 and TNFR2 signalling in a mouse model of total parenteral nutrition [PDF]
, 2013 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99095/1/jphysiol.2013.253518 ...
Feng, Yongjia, Teitelbaum, Daniel H.
core +1 more source