Results 11 to 20 of about 132,079 (287)

Benzodiazepine use in physicians: retrospective 5-year nationwide study in Taiwan [PDF]

BJPsych Open
Background Benzodiazepine use among physicians is an important public health issue related to physicians’ well-being and patient safety. Aims This study aimed to evaluate the patterns and correlates of benzodiazepine use in physicians by comparing ...
Wan-Ju Cheng, Yin-Chieh Chuang, Hsuan-Ching Wang, Hei-Tung Yip, Cheng-Li Lin, Cynthia Wei-Sheng Lee   +5 more
doaj   +2 more sources

Long-term consequences of benzodiazepine-induced neurological dysfunction: A survey.

PLoS ONE, 2023
BackgroundAcute benzodiazepine withdrawal has been described, but literature regarding the benzodiazepine-induced neurological injury that may result in enduring symptoms and life consequences is scant.ObjectiveWe conducted an internet survey of current ...
Alexis D Ritvo, D E Foster, Christy Huff, A J Reid Finlayson, Bernard Silvernail, Peter R Martin   +5 more
doaj   +3 more sources

Supporting safe and gradual reduction of long‐term benzodiazepine receptor agonist use: Development of the SAFEGUARDING‐BZRAs toolkit using a codesign approach

Health Expectations, 2022
Introduction Long‐term benzodiazepine receptor agonist (BZRA) use persists in healthcare settings worldwide and poses risks of patient harm. Objective This study aimed to develop an intervention to support discontinuation of long‐term BZRA use among ...
Tom Lynch, Cristín Ryan, Colin Bradley, D. Foster, Christy Huff, Sharon Hutchinson, Nicole Lamberson, Lily Lynch, Cathal Cadogan   +8 more
doaj   +1 more source

The Frequency of Benzodiazepine Use in the Isparta Province

Psychiatry and Clinical Psychopharmacology, 2021
Objective: In the present study, we aimed to determine the frequency of benzodiazepine prescriptions to patients with psychiatric disorders in Isparta Province, Turkey.
Abdullah Akpinar, Ayse Rumeysa Yaman, Kadir Karakus, Inci Meltem Atay, Kadir Demirci   +4 more
doaj   +1 more source

GABAA receptor subtypes and benzodiazepine use, misuse, and abuse

Frontiers in Psychiatry, 2023
Benzodiazepines have been in use for over half a century. While they remain highly prescribed, their unfavorable side-effect profile and abuse liability motivated a search for alternatives.
Elif Engin, Elif Engin
doaj   +1 more source

Exploring trends in benzodiazepine-positive fatal drug overdoses in Tennessee, 2019–2021

Annals of Medicine, 2023
Background Benzodiazepine-positive overdoses increased between 2019 and 2021 in Tennessee. We sought to determine the changes in the number and characteristics of prescription and illicit benzodiazepine-positive fatal drug overdoses during this period ...
Jenna Moses, Jessica Korona-Bailey, Sutapa Mukhopadhyay   +2 more
doaj   +1 more source

A review on the chemistry and pharmacological properties of benzodiazepine motifs in drug design

Arab Journal of Basic and Applied Sciences, 2022
Benzodiazepines are an important class of heterocyclic compounds in organic chemistry. They are known for their diverse physicochemical and biological properties.
Olayinka O. Tolu-Bolaji, Samuel O. Sojinu, Adebola P. Okedere, Olayinka O. Ajani   +3 more
doaj   +1 more source

Comparison of Nitrous Oxide-Oxygen as Inhalation Agent, Midazolam, Ketamine alone and in Combination as Oral Sedative Agents for In-office Paediatric PatientsA Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: In-office pharmacological sedation techniques are best applied to manage an extremely fearful preschooler, especially during primary dentition or a child’s early mixed dentition period.
MONIKA NAGPAL, MOHAN LAL KHATRI, ANIL GUPTA, ANKIT SRIVASTAVA, SHALINI GARG   +4 more
doaj   +1 more source

Treatment of concurrent etizolam and tianeptine withdrawal following accidental overdose [PDF]

Mental Health Clinician, 2023
Background: The availability of nonapproved psychoactive substances with addiction potential from internet sources poses a significant threat to public health.
Marija Markovic, PharmD, BCPP, Dania Niwash, PA-C   +1 more
doaj   +1 more source

TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria [PDF]

, 2016
The 18-kDa translocator protein (TSPO) localizes in the outer mitochondrial membrane (OMM) of cells and is readily up-regulated under various pathological conditions such as cancer, inflammation, mechanical lesions and neurological diseases. Able to bind
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core   +1 more source