Background Little is known about benzodiazepine and opioid-benzodiazepine co-dispensing patterns among pregnant women. Understanding these patterns is necessary to mitigate high-risk medication use during pregnancy.
Danya M. Qato, Aakash Bipin Gandhi
doaj +1 more source
Hemadsorption: A New Therapeutic Option for Selected Cases of Bromazepam Intoxication
Benzodiazepine ingestion is frequent in patients admitted to ICU for intoxications. Generally, a supportive approach by securing the airway, breathing, and circulation is sufficient.
Michaël Mekeirele +4 more
doaj +1 more source
Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen +5 more
core +2 more sources
Background Benzodiazepines are frequently prescribed to elderly patients' despite concerns about adverse effects leading to injurious falls. Previous studies have not investigated the extent to which patients with pre-existing risk factors for falls are ...
Sylvestre Marie-Pierre +4 more
doaj +1 more source
Carbon dioxide test as an additional clinical measure of treatment response in panic disorder [PDF]
OBJECTIVE: We aim to determine if a treatment with a dose of clonazepam - 2 mg/day, for 6 weeks, blocks spontaneous panic attacks and the ones induced by the inhalation of 35% carbon dioxide (CO2) in panic disorder (PD) patients.
Alexandre M. Valença +4 more
doaj +1 more source
Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data from the Veterans Aging Cohort Study [PDF]
Background: Insomnia is associated with increased cardiovascular disease (CVD) risk in the general population and is highly prevalent in people with HIV. The CVD risk conferred by insomnia in the HIV population is unknown.
Bedimo, Roger J. +12 more
core +1 more source
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] [PDF]
Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ.
A Jablensky +21 more
core +3 more sources
Benzodiazepine Use Before Conception and Risk of Ectopic Pregnancy
Introduction Ectopic pregnancy occurs in 1% to 2% of the all recognized pregnancies, yet half of women who have an ectopic pregnancy do not have any known risk factors.
Elizabeth Wall-Wieler +5 more
doaj +1 more source
Background: Gamma-aminobutyric acid (GABA) type A receptors are positively allosterically modulated by benzodiazepine binding, leading to a potentiated response to GABA.
Tomonori Furukawa +8 more
doaj +1 more source
Metabolism and toxicity of two new benzodiazepine-type antileishmanial agents in hepatocytes and macrophages [PDF]
With increasing reports of resistance of Leishmania to antimonials (Thakur et al., 2004) and other traditional antileishmanial drugs, the need for the discovery of new antileishmanial agents is rising.
Clarke, R. +5 more
core +1 more source

