Results 21 to 30 of about 1,026 (107)
Additional file 20 of Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET
, 2022 Additional file 20. Coefficients of determination (r2) and slopes of parametric [11C]UCB-J BPND and R1 against corresponding SRTM estimates using 90 minutes data. All the Hammers ROIs were included for this analysis.Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M., Hollander-Meeuwsen, Marijke den, de Vries, Erik F. J., Glaudemans, Andor W. J. M., Feltes, Paula Kopschina, García, David Vállez, Verfaillie, Sander C. J., Wolters, Emma E., Sweeney, Steven P., Ryan, J. Michael, Ivarsson, Magnus, Lynch, Berkley A., Schober, Patrick, Scheltens, Philip, Schuit, Robert C., Windhorst, Albert D., De Deyn, Peter P., van Berckel, Bart N. M., Golla, Sandeep S. V. +20 moreopenaire +1 more sourceWONOEP appraisal: Biomarkers and treatment strategies beyond the synapse
Epilepsia, Volume 67, Issue 10, Page 5026-5041, October 2026.Abstract
Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.Mirte Scheper, Zining Liu, Aristea S. Galanopoulou, Gernot Hlauschek, Benjamin Sinclair, Wai Lam Leung, Stefanie Dedeurwaerdere, Elisabeth Doran, Solomon L. Moshé, David C. Henshall, Ozlem Akman, Pablo M. Casillas‐Espinosa +11 morewiley +1 more sourceAdditional file 16 of Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET
, 2022 Additional file 16. TRT (%) values estimated for specific brain regions (grey matter) are presented for SA VT and K1.Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M., Hollander-Meeuwsen, Marijke den, de Vries, Erik F. J., Glaudemans, Andor W. J. M., Feltes, Paula Kopschina, García, David Vállez, Verfaillie, Sander C. J., Wolters, Emma E., Sweeney, Steven P., Ryan, J. Michael, Ivarsson, Magnus, Lynch, Berkley A., Schober, Patrick, Scheltens, Philip, Schuit, Robert C., Windhorst, Albert D., De Deyn, Peter P., van Berckel, Bart N. M., Golla, Sandeep S. V. +20 moreopenaire +1 more sourceAdditional file 17 of Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET
, 2022 Additional file 17. TRT (%) values estimated for specific brain regions (grey matter) are presented for SRTM2 BPND and R1.Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M., Hollander-Meeuwsen, Marijke den, de Vries, Erik F. J., Glaudemans, Andor W. J. M., Feltes, Paula Kopschina, García, David Vállez, Verfaillie, Sander C. J., Wolters, Emma E., Sweeney, Steven P., Ryan, J. Michael, Ivarsson, Magnus, Lynch, Berkley A., Schober, Patrick, Scheltens, Philip, Schuit, Robert C., Windhorst, Albert D., De Deyn, Peter P., van Berckel, Bart N. M., Golla, Sandeep S. V. +20 moreopenaire +1 more sourceGLP‐1 receptor agonists in Alzheimer's disease and MCI: a meta‐analysis
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 4, October/December 2026.Abstract INTRODUCTION
Alzheimer's disease (AD) is the leading cause of dementia in older individuals and remains a major clinical and socioeconomic burden. Despite the success of anti‐amyloid therapies in reducing biomarker burden, more effective and safer treatments are still needed.Ryan G. P. Siqueira, Carlotta Ranalli, Duygu Yılmaz, Meire da Silva, Bernardo Raposo Pinel Maltez, Giovanni Gosch Berton, Jeffrey L. Cummings +6 morewiley +1 more sourceAdditional file 21 of Validation and test–retest repeatability performance of parametric methods for [11C]UCB-J PET
, 2022 Additional file 21. TRT (%) values estimated for whole brain (grey matter) are presented for each parametric method using 90 minutes data.Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M., Hollander-Meeuwsen, Marijke den, de Vries, Erik F. J., Glaudemans, Andor W. J. M., Feltes, Paula Kopschina, García, David Vállez, Verfaillie, Sander C. J., Wolters, Emma E., Sweeney, Steven P., Ryan, J. Michael, Ivarsson, Magnus, Lynch, Berkley A., Schober, Patrick, Scheltens, Philip, Schuit, Robert C., Windhorst, Albert D., De Deyn, Peter P., van Berckel, Bart N. M., Golla, Sandeep S. V. +20 moreopenaire +1 more sourceAlzheimer's disease heterogeneity and co‐pathologies: Defining novel targets, biomarkers, modalities, and research methodologies
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.Abstract Alzheimer's disease (AD) is a biologically heterogeneous condition with vascular, proteinopathic, metabolic, and immune processes jointly shaping its clinical expression, trajectory of progression, and response to therapeutic intervention.Malú Gámez Tansey, Sasha Bozeat, Peter Ackerman, Alireza Atri, Christopher J. Barnum, Patrik Brundin, Carlos Abreu de Carvalho, Adam S. Fleisher, Ana Graf, Elizabeth Head, Geoffrey A. Kerchner, Hartmuth C. Kolb, Akihiko Koyama, Mariel Kozberg, Cheryl E. G. Leyns, Jorge J. Llibre‐Guerra, Niklas Mattsson‐Carlgren, David McKissock, Melissa E. Murray, Liana S. Rosenthal, Carrie Rubel, Suzanne E. Schindler, Julie A. Schneider, Adam J. Schwarz, Kirsten M. Scott, Tamara Seredenina, Duygu Tosun, Rebecca L. Wallings, Hong Wang, Donna M. Wilcock, Maria Carrillo, Simin Mahinrad, Christopher J. Weber +32 morewiley +1 more sourceCerebrospinal fluid protein elevations in Alzheimer's disease are dissociated from immune cell composition
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.Abstract INTRODUCTION
Elevated cerebrospinal fluid (CSF) inflammatory proteins have been reported in Alzheimer's disease (AD), yet whether they reflect peripheral immune cell infiltration or central nervous system (CNS)–intrinsic pathological processes remains unclear. We tested whether AD exhibits a distinct CSF protein signature and how it relates to Sina Zaic, Theresa König, Omar Keritam, Valérie Faber, Katharina Seifried, Sara Silvaieh, Nik Krajnc, Raphael Wurm, Tandis Parvizi, Stefan Macher, Paulus Rommer, Fritz Leutmezer, Gabriel Bsteh, Elisabeth Stögmann, Thomas Berger, Tobias Zrzavy +15 morewiley +1 more sourceAdditional file 2 of Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET
, 2022 Additional file 2. Automated region of interest definition on mCI PET Images - (A) A single slice of a cropped anatomical CT image. (B) Binarized cropped CT image including voxels including vertebrae. (C) Closed, binarized cropped CT image including vertebrae and spinal cavity. (D) Difference image between (C) and (D) including spinal cavity.Rossano, Samantha, Toyonaga, Takuya, Bini, Jason, Nabulsi, Nabeel, Ropchan, Jim, Cai, Zhengxin, Huang, Yiyun, Carson, Richard E. +7 moreopenaire +1 more sourceMovement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1399-1417, June 2026.Abstract Background
Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective
We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett +6 morewiley +1 more source
