Results 1 to 10 of about 999,551 (181)
Intestinal α-Defensins Play a Minor Role in Modulating the Small Intestinal Microbiota Composition as Compared to Diet [PDF]
Microbiology Spectrum, 2023 The intestinal microbiota is at the interface between the host and its environment and thus under constant exposure to host-derived and external modulators.
Fabiola Puértolas-Balint +1 more
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α-Defensins Promote Bacteroides Colonization on Mucosal Reservoir to Prevent Antibiotic-Induced Dysbiosis [PDF]
Frontiers in Immunology, 2020 In addition to their established functions in host defense, accumulating evidence has suggested an emerging role for antimicrobial proteins (AMPs) in shaping commensal microbiota.
Jiayao Ou +11 more
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Variations in the interaction of human defensins with Escherichia coli: Possible implications in bacterial killing. [PDF]
PLoS ONE, 2017 Human α and β-defensins are cationic antimicrobial peptides characterized by three disulfide bonds with a triple stranded β-sheet motif. It is presumed that interaction with the bacterial cell surface and membrane permeabilization by defensins is an ...
Basil Mathew, Ramakrishnan Nagaraj
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Scots pine defensins inhibit Ips acuminatus α-amylase activity [PDF]
Біологічні студії, 2023 Background. Pine bark beetle Ips acuminatus (Gyllenhal, 1827) is one of the most harmful pests of pine trees as it affects the phloem of the upper part of the stem and branches, disrupting the flow of nutrients and water to the crown. I. acuminatus feeds
Yurii Yusypovych +7 more
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A Novel Approach on Leukodepletion Filters: Investigation of Synergistic Anticancer Effect of Purified α-Defensins and Nisin [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: There are number of reports available regarding defensins activity against mammalian cells besides their antimicrobial and immune regulatory activities.
Niloofar Sasani +3 more
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Egyptian Rheumatology and Rehabilitation, 2020 Background Behcet’s disease (BD) is associated with uveitis, oral ulcers, genital ulcers and arthritis. Enhanced activity of innate immunity components, such as neutrophils, natural killer (NK) cells and endothelial cells, is a prominent feature of BD ...
Reham M. Shaat +4 more
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Characterization of two novel defensins Han-Def1 and Han-Def2 from Hyalomma anatolicum [PDF]
Frontiers in MicrobiologyBackgroundHyalomma anatolicum is an important vector of veterinary and zoonotic pathogens, posing potential threats to livestock production and public health.
Tingxiang Luo +22 more
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International Journal of Infectious Diseases, 2023 Objectives: Nosocomial ventriculitis is a difficult infectious condition to diagnose given that typical cerebral spinal fluid (CSF) parameters, commonly used in the diagnosis of meningitis, lack sensitivity and specificity in nosocomial ventriculitis ...
James B. Doub
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Respiratory Research, 2023 Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder associated with a 5–tenfold decrease in lung levels of alpha-1-antitrypsin (AAT) and an increased risk for obstructive lung disease.
Jungnam Lee +5 more
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The evolution of antimicrobial peptides in Chiroptera
Frontiers in Immunology, 2023 High viral tolerance coupled with an extraordinary regulation of the immune response makes bats a great model to study host-pathogen evolution. Although many immune-related gene gains and losses have been previously reported in bats, important gene ...
Francisco X. Castellanos +15 more
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