Results 171 to 180 of about 57,365 (244)
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Identification of a novel nonsense mutation in α-galactosidase A that causes Fabry disease in a Chinese family. [PDF]
Peng Y +7 more
europepmc +1 more source
Abstract Cryo‐electron tomography (cryo‐ET) enables structural characterization of biomolecules under near‐native conditions. Existing approaches for interpreting the resulting three‐dimensional volumes are computationally expensive and have difficulty interpreting density associated with small proteins/complexes.
Chengxuan Li +9 more
wiley +1 more source
Crystal Structure of Bifidobacterium bifidum Glycoside Hydrolase Family 110 α-Galactosidase Specific for Blood Group B Antigen. [PDF]
Kashima T +5 more
europepmc +1 more source
First report of Bordetella bronchiseptica in the reproductive tract of Brazilian mares. Uterine lavage samples from mares with endometritis and infertility were positive by culture, PCR (237 bp flaA), sequencing and phylogenetic analysis. Isolates showed multidrug resistance, emphasizing the relevance of this pathogen in equine reproductive disorders ...
Samira Salim Mello Gallo +5 more
wiley +1 more source
Comparative study on incorporation of three recombinant human α-galactosidase A drugs (agalsidases) into cultured fibroblasts and organs/tissues of Fabry mice. [PDF]
Tsukimura T +3 more
europepmc +1 more source
ABSTRACT Yogurt is one of the most technologically mature fermented dairy products on the market, traditionally prepared using the two lactic acid bacteria (LAB) Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus. Global demand for yogurt continues to rise, driven by consumer interest in healthy, high‐protein diets with as few ...
Shuangqing Zhao +2 more
wiley +1 more source
Misfolding of Lysosomal α-Galactosidase a in a Fly Model and Its Alleviation by the Pharmacological Chaperone Migalastat. [PDF]
Braunstein H +5 more
europepmc +1 more source
Nutritional quality traits in pea seed: Current knowledge and opportunities for genetic improvement
This comprehensive review on nutritional traits in pea (Pisum sativum L.) summarizes the literature on genetic improvement of this highly nutritious and environmentally sustainable crop for different end‐uses. Abstract Pea is a major pulse crop valued for its high protein, carbohydrate, and mineral content, as well as its agronomic role in sustainable ...
Ahmed O. Warsame, Janneke Balk
wiley +1 more source
Yoda1‐induced Piezo1 activation enhances Piezo1‐Cx43 interaction upon mechanical stimulation, triggering PI3K‐Akt signaling to drive Cx43 phosphorylation and hemichannel opening. These events elevate PGE2 release, suppress SOST expression in senescent osteocytes, and ultimately enhance bone anabolism on the endosteal surface.
Dezhi Zhao +10 more
wiley +1 more source

