Results 151 to 160 of about 937,878 (172)
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian +3 more
wiley +1 more source
ABSTRACT The increasing demands of elite sports reduce recovery time, impair performance, and increase injury risk. Efficient lactate transport is essential for postexercise recovery. Capacitive resistive electric transfer (CRET) therapy enhances deep tissue heating, induces vasodilation, and promotes circulation. To evaluate whether adding active CRET
Max Canet‐Vintró +6 more
wiley +1 more source
Mechanistic diagram of the hepatoprotective effect of Tgy‐N on D‐gal‐induced senescent C57BL/6 mice (“→” indicates activation, and “⊣” indicates inhibition). ABSTRACT This research aimed to investigate the hepatoprotective and anti‐senescence effects of Nongxiang‐type Tieguanyin (Tgy‐N) on D‐galactose (D‐gal)‐induced aging C57BL/6 mice and to elucidate
Weihong Chen +11 more
wiley +1 more source
Gastrodia elata polysaccharide (GEP) alleviates aging in mice by activating the Nrf2/Keap1 antioxidant signaling, inhibiting the TLR4/NF‐κB‐driven neuroinflammation, remodeling gut microbiota, and restoring intestinal‐barrier integrity. Synergistic regulation of oxidation, inflammation, and gut homeostasis underpins its anti‐aging potential for ...
Huihuang Shi +5 more
wiley +1 more source
Small Molecule Therapeutic Approaches With a Greater Focus on Hearing Loss: A Review
ABSTRACT Background and Aims Hearing loss (HL) is one of the most common sensory impairments worldwide and has substantial effects on quality of life and daily functioning. Although cochlear implants and hearing aids have markedly improved the management of hearing impairment, these devices do not directly address the underlying pathogenic mechanisms ...
Maryam Naghinejad +5 more
wiley +1 more source
1‐AP induced genomic instability and senescence in RTECs sustaining BRD4‐dependent SAPS transcription and paracrine fibroblast activation. Targeting BRD4 may treat pollution‐related CKD. ABSTRACT Epidemiological evidence links environmental pollution to chronic kidney disease (CKD).
Atul Katarkar +6 more
wiley +1 more source
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou +12 more
wiley +1 more source
ABSTRACT Tendinopathies comprise half of musculoskeletal injuries, yet medical treatments are lacking. Orthobiologics are novel therapeutics developed to address this gap, with extracellular vesicles (EVs) being a promising prospect. However, we lack a complete understanding of how EVs affect regeneration, both endogenously and as a tool for augmenting
Gabrielle Gilmer +5 more
wiley +1 more source
Abstract BACKGROUND Preharvest light management is increasingly used to enhance yield and fruit quality in soilless systems, yet its effects on unripe melon fruits remain poorly understood. This study evaluated the impact of supplemental red–blue light‐emitting diode (LED) lighting applied during cultivation in a closed‐cycle hydroponic system on ...
Onofrio Davide Palmitessa +7 more
wiley +1 more source
Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley +1 more source

