Diagnostic value of BTG2 and its immunoregulatory mechanism in IgAN. This study reveals that BTG2 improves immune microenvironment dysregulation, attenuates inflammation, and reduces fibrosis by promoting the expansion of T follicular helper cells, inducing macrophage polarization toward an M2 anti‐inflammatory phenotype, and inhibiting the TGF‐β1 ...
Min Kou +4 more
wiley +1 more source
Assessing α-galactosidase OmAGAL2 inhibitors and their impact on germination and sugar profiles in <i>Orobanche minor</i>. [PDF]
Onitsuka M +5 more
europepmc +1 more source
Cardiomyopathy associated with the Ala143Thr variant of the α-galactosidase A gene. [PDF]
Valtola K +9 more
europepmc +1 more source
Impact of combined α-galactosidase and xylanase enzymes on growth performance, nutrients digestibility, chyme viscosity, and enzymes activity of broilers fed corn-soybean diets. [PDF]
Liu X +5 more
europepmc +1 more source
Occurrence of infusion associated reactions and anti‐drug antibodies in enzyme replacement therapy for Fabry disease and the effect of preventive measures. ABSTRACT Male patients with the classical phenotype of Fabry disease (FD) are at risk of developing inhibiting antidrug antibodies (iADAs) against recombinant α‐galactosidase‐A, administered in the ...
Maud Janssens +5 more
wiley +1 more source
Optimizing α-galactosidase A enzyme cutoff for Fabry disease screening in chronic kidney disease patients: a single-center reassessment of diagnostic yield and cost-effectiveness. [PDF]
Tsai SF, Wu MJ, Hsieh HH, Chen CH.
europepmc +1 more source
ABSTRACT Adult patients with inherited metabolic diseases are often overlooked. Limited data on this population hinder adequate planning of their clinical and social care. In this retrospective, observational, cross‐sectional service evaluation study, we reviewed the electronic medical records of adult patients with inherited neurometabolic diseases ...
Boel Ernerdahl +2 more
wiley +1 more source
New α-galactosidase-inhibiting aminohydroxycyclopentanes. [PDF]
Weber P +7 more
europepmc +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Silencing of the Alkaline α-Galactosidase Gene <i>CsAGA1</i> Impairs Root and Gall Development in Cucumber upon <i>Meloidogyne incognita</i> Infection. [PDF]
Ji T +5 more
europepmc +1 more source

