Results 161 to 170 of about 937,878 (172)

Nursery pig growth response to feed ingredients and feed additives: I). Spray-dried blood plasma vs. spray-dried egg effect on nursery pig growth performance II). Effect of α-galactosidase and citric acid on nursery pig growth performance when added to a corn-soybean meal diet

, 2018
openaire   +2 more sources

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

MedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu, Jie Yu, Ying Chen, Shengfang Ge, Lin Ye, Yefei Wang, Yixiong Zhou, Renbing Jia   +7 more
wiley   +1 more source

Mitochondrial Transplantation Rejuvenates Aging Heart by Restoring Mitophagy Flux via the HIF‐3α‐BNIP3 Axis

Aging Cell, Volume 25, Issue 10, October 2026.
Aging heart shows mitophagy flux congestion and mitochondrial dysfunction. Aberrant activation of the HIF‐3α‐BNIP3 axis induces mitophagy flux congestion in the aging heart. Mitochondrial transplantation rectifies the HIF‐3α‐BNIP3 axis and restores mitophagy flux by elevating ATP production in the aging heart.
Ning Jin, Li Zhou, Haixia Gui, Jingjing Tang, Xiaozhen Huang, Wenting Wang, Guorong Jin, Haiqin Cheng, Yuxiang Liang, Xinyi Geng, Zhiwei Peng, Hong Zhao, Zhizhen Liu, Jun Xie   +13 more
wiley   +1 more source

Time‐Restricted Feeding Delays Cardiovascular Aging by Increasing Acetic Acid Through Remodeling Gut Microbiota

Aging Cell, Volume 25, Issue 10, October 2026.
Time‐restricted feeding delays vascular aging and cardiac remodeling by fostering a symbiotic gut microbiota that bolsters barrier function and amplifies short‐chain fatty acid production. ABSTRACT Time‐restricted feeding (TRF) restricts food intake to daily windows, yet its efficacy against vascular aging and underlying mechanisms remain unclear. Here,
Man Liu, Mandi Luo, Yangyang Huang, Tianyi Ji, Yuman Wang, Qian Wang, Jie Huang, Tao Jiang, Cuntai Zhang, Tao Mi, Mian Cheng   +10 more
wiley   +1 more source

Single‐Cell Mapping Identifies Aging‐Associated Neutrophil Remodeling Across Multiple Organs

Aging Cell, Volume 25, Issue 10, October 2026.
Single‐cell transcriptomic profiling across multiple organs identifies aging reshapes neutrophil differentiation from the bone marrow to peripheral tissues. Computation analysis identifies an age‐enriched Neu06‐IL6 neutrophil state and predicts IL‐6 as one of a candidate regulator for neutrophil remodeling.
Yuman Wang, Teding Chang, Yangguang Fu, Guangyu Liang, Huicheng Liu, Le Zhang, Jinhua Yan, Man Liu, Anding Liu, Cuntai Zhang   +9 more
wiley   +1 more source

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

Aging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang, Rahagir Salekeen, Carolina Soto‐Palma, Qiuming Wu, Yuanjun He, Osama Elsallabi, Bilel Bdiri, Brian Hughes, Allancer Nunes, Wandi Xu, Borui Zhang, Abdalla Mohamed, Sara J. McGowan, Luise Angelini, Ryan O'Kelly, Theodore M. Kamenecka, Laura J. Niedernhofer, Paul D. Robbins   +17 more
wiley   +1 more source

Targeting Ero1L by Parthenolide Alleviates Cellular Senescence and Fibrosis of Localized Scleroderma by Regulating Mitochondria‐Associated Endoplasmic Reticulum Membranes Stabilization

Aging Cell, Volume 25, Issue 10, October 2026.
PTL inhibits cell senescence and alleviates fibrosis of Los by regulating Ero1L‐mediated mitochondria‐associated endoplasmic reticulum membranes stabilization. ABSTRACT Mitochondrial dysfunction drives scleroderma pathogenesis. The mitochondria‐associated endoplasmic reticulum membrane (MAM) regulates mitochondrial function.
Fei Wang, Ru Xing, Meijuan Xie, Yimin Qin, Yunchao Zhang, Dan Cao, Gu He, Xiaoyan Lyu   +7 more
wiley   +1 more source

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SEPARATION OF ENZYME SOLUTION OF SOUR CHERRY (PRUNUS CERASUS L.) AND IDENTIFICATION OF β-GALACTOSIDASE

Acta Horticulturae, 2005
Different sour cherry cultivars (cv. 'Erdi botermo', 'Kantorjanosi' and 'Pandy 279') were harvested than stored for 30 days at 4-6°C, 89-90% RH. The absorbance pattern of juice was different between fresh and stored fruits, especially in case of cv. 'Kantorjanosi'. No remarkable differences was found in cv. 'Erdi botermo' fresh and stored.
E. Kovács, E. Németh-Szerdahelyi, S. Horváth   +2 more
openaire   +1 more source

Optimised N-acetyl-d-lactosamine synthesis using Thermus thermophilus β-galactosidase in bio-solvents

Tetrahedron, 2013
Ministerio de Ciencia e Innovacion; UCM/ Santander; Universidad Nacional de Costa ...
Sandoval, Manuel, Civera, Concepción, Berenguer, José, García-Blanco, Franscico, Hernáiz, María J.   +4 more
openaire   +2 more sources

GM1 gangliosidosis and Morquio B disease: expression analysis of missense mutations affecting the catalytic site of acid β-galactosidase

Human Mutation, 2009
Alterations in GLB1, the gene coding for acid beta-D-galactosidase (beta-Gal), can result in GM1 gangliosidosis (GM1), a neurodegenerative disorder, or in Morquio B disease (MBD), a phenotype with dysostosis multiplex and normal central nervous system (CNS) function.
Hofer, Doris, Paul, Karl, Fantur, Katrin, Beck, Michael, Bürger, Friederike, Caillaud, Catherine, Fumić, Ksenija, Ledvinova, Jana, Lugowska, Agnieszka, Michelakakis, Helen, Radeva, Briguita, Ramaswami, Uma, Plečko, Barbara, Paschke, Eduard   +13 more
openaire   +3 more sources