Results 141 to 150 of about 1,809,550 (296)

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease.

Molecular Genetics and Metabolism, 2015
Fabry disease is an X-linked recessive disorder caused by the loss of function of the lysosomal enzyme α-Galactosidase-A. Although two enzyme replacement therapies (ERTs) are commercially available, they may not effectively reverse some of the Fabry ...
T. Kizhner, Yaniv Azulay, Mariana Hainrichson, Yoram Tekoah, Gil Arvatz, Avidor Shulman, Ilya Ruderfer, D. Aviezer, Y. Shaaltiel   +8 more
semanticscholar   +1 more source

Functional Identification of Arabidopsis ATSIP2 (At3g57520) as an Alkaline α-Galactosidase with a Substrate Specificity for Raffinose and an Apparent Sink-Specific Expression Pattern [PDF]

, 2017
Arabidopsis ATSIP2 has recently been suggested to be a raffinose synthase gene. However, it has high amino acid identity to functionally characterized alkaline α-galactosidases from Cucumis melo and Zea mays.
Egert, Aurélie, Keller, Felix, Peters, Shaun, Stieger, Bruno   +3 more
core  

Mannose receptor-mediated delivery of moss-made α-galactosidase A efficiently corrects enzyme deficiency in Fabry mice

Journal of Inherited Metabolic Disease, 2015
Enzyme replacement therapy (ERT) is an effective treatment for several lysosomal storage disorders (LSDs). Intravenously infused enzymes are taken up by tissues through either the mannose 6-phosphate receptor (M6PR) or the mannose receptor (MR).
Jinsong Shen, A. Busch, Taniqua S. Day, Xing‐Li Meng, Chun I Yu, Paulina Dabrowska-Schlepp, Benjamin Fode, Holger Niederkrüger, S. Forni, Shuyuan Chen, R. Schiffmann, T. Frischmuth, A. Schaaf   +12 more
semanticscholar   +1 more source

Aging and periodontitis increase brain dissemination of oral bacteria

Journal of Periodontology, EarlyView.
Abstract Background The microbiome is a dynamic system that changes throughout life. Studies have revealed the relationship between periodontal disease and the oral microbiota; however, the impact of periodontal disease on the expression of senescence markers and on the inflammaging of the oral and systemic microbiome remains unclear.
Ozge Unlu, Tsute Chen, Nil Yakar, Zeliha Guney, Bruce Paster, Isabel Carreras, Alpaslan Dedeoglu, Alpdogan Kantarci   +7 more
wiley   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

CreA-mediated carbon catabolite repression of β-galactosidase formation inAspergillus nidulansis growth rate dependent [PDF]

FEMS Microbiology Letters, 2004
Hedvig Ilyés, Erzsébet Fekete, Levente Karaffa, Éva Fekete, Erzsébet Sándor, Attila Szentirmai, Christian P. Kubicek   +6 more
openaire   +1 more source

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

PROTEOMICS, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir, Karina Biskup, Michael Sittinger, Rudolf Tauber, Véronique Blanchard   +4 more
wiley   +1 more source

Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model

Frontiers in Molecular Neuroscience, 2018
Fabry disease is an X-linked lysosomal storage disorder with involvement of the nervous system. Accumulation of glycosphingolipids within peripheral nerves and/or dorsal root ganglia results in pain due to small-fiber neuropathy, which affects the ...
Kai K. Kummer, Theodora Kalpachidou, Michaela Kress, Michiel Langeslag   +3 more
doaj   +1 more source

Immobilized preparation of cold-adapted and halotolerant Antarctic β-galactosidase as a highly stable catalyst in lactose hydrolysis [PDF]

FEMS Microbiology Ecology, 2007
Krzysztof Makowski, Aneta Białkowska, Mirosława Szczęsna-Antczak, Halina Kalinowska, Józef Kur, Hubert Cieśliński, Marianna Turkiewicz   +6 more
openaire   +1 more source