Results 11 to 20 of about 1,809,550 (296)

Optimization of Saccharomyces cerevisiae α-galactosidase production and application in the degradation of raffinose family oligosaccharides. [PDF]

Microb Cell Fact, 2019
Backgroundα-Galactosidases are enzymes that act on galactosides present in many vegetables, mainly legumes and cereals, have growing importance with respect to our diet.
Álvarez-Cao ME, Cerdán ME, González-Siso MI, Becerra M.   +3 more
europepmc   +2 more sources

Biochemical characterization and insights into the potency of the acidic Aspergillus niger NRC114 purified α-galactosidase in removing raffinose family oligosaccharides from soymilk yogurt [PDF]

BMC Biotechnology, 2023
Background Because humans lack α-galactosidase, foods containing certain oligosaccharides from the raffinose family, such as soybeans and other legumes, may disrupt digestion and cause flatulence.
Abdelmageed M. Othman, Ali M. Elshafei, Maysa A. Elsayed, Gamil E. Ibrahim, Mohamed M. Hassan, Nayra S. Mehanna   +5 more
doaj   +2 more sources

Detection of α-Galactosidase A Reaction in Samples Extracted from Dried Blood Spots Using Ion-Sensitive Field Effect Transistors [PDF]

Sensors
Fabry disease is a lysosomal storage disorder caused by a significant decrease in the activity or absence of the enzyme α-galactosidase A. The diagnostics of Fabry disease during newborn screening are reasonable, due to the availability of enzyme ...
Alexander Kuznetsov, Andrey Sheshil, Eugene Smolin, Vitaliy Grudtsov, Dmitriy Ryazantsev, Mark Shustinskiy, Tatiana Tikhonova, Irakli Kitiashvili, Valerii Vechorko, Natalia Komarova   +9 more
doaj   +2 more sources

Oral Migalastat HCl Leads to Greater Systemic Exposure and Tissue Levels of Active α-Galactosidase A in Fabry Patients when Co-Administered with Infused Agalsidase [PDF]

PLoS ONE, 2015
Migalastat HCl (AT1001, 1-Deoxygalactonojirimycin) is an investigational pharmacological chaperone for the treatment of α-galactosidase A (α-Gal A) deficiency, which leads to Fabry disease, an X-linked, lysosomal storage disorder. The currently approved,
D. Warnock, D. Bichet, M. Holida, O. Goker-Alpan, K. Nicholls, Mark Thomas, F. Eyskens, S. Shankar, Mathews Adera, S. Sitaraman, R. Khanna, J. Flanagan, B. Wustman, J. Barth, C. Barlow, K. Valenzano, D. Lockhart, P. Boudes, F. Johnson   +18 more
semanticscholar   +10 more sources

Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease. [PDF]

J Biol Chem, 2018
α-Galactosidases (EC 3.2.1.22) are retaining glycosidases that cleave terminal α-linked galactose residues from glycoconjugate substrates. α-Galactosidases take part in the turnover of cell wall–associated galactomannans in plants and in the lysosomal ...
Kytidou K, Beekwilder J, Artola M, van Meel E, Wilbers RHP, Moolenaar GF, Goosen N, Ferraz MJ, Katzy R, Voskamp P, Florea BI, Hokke CH, Overkleeft HS, Schots A, Bosch D, Pannu N, Aerts JMFG.   +16 more
europepmc   +2 more sources

Improving the Secretory Expression of an -Galactosidase from Aspergillus niger in Pichia pastoris. [PDF]

PLoS ONE, 2016
α-Galactosidases are broadly used in feed, food, chemical, pulp, and pharmaceutical industries. However, there lacks a satisfactory microbial cell factory that is able to produce α-galactosidases efficiently and cost-effectively to date, which prevents ...
Xianliang Zheng, Bo Fang, Dongfei Han, Wenxia Yang, Feifei Qi, Hui Chen, Shengying Li   +6 more
doaj   +2 more sources

Characterization of β-galactosidase and α-galactosidase activities from the halophilic bacterium Gracilibacillus dipsosauri

Annals of Microbiology, 2021
Purpose Gracilibacillus dipsosauri strain DD1 is a salt-tolerant Gram-positive bacterium that can hydrolyze the synthetic substrates o-nitrophenyl-β-d-galactopyranoside (β-ONP-galactose) and p-nitrophenyl-α-d-galactopyranoside (α-PNP-galactose).
Charles E. Deutch, Amy M. Farden, Emily S. DiCesare   +2 more
doaj   +1 more source

Activity of α-d-Galactosidase in Long-Stored Seeds of Vicia hirsuta

Agriculture, 2023
Mature seeds of many crop species contain substantial amounts of soluble carbohydrates, including raffinose family oligosaccharides (RFOs) and cyclitol galactosides (Gal-C).
Ewa Gojło
doaj   +1 more source

Purification and characterization of a β-galactosidase fromSclerotinia sclerotiorum [PDF]

FEMS Microbiology Letters, 1992
Sclerotinia sclerotiorum secretes β-galactosidase, giving very low activity when cultivated in a medium with glucose as the carbon source. This production is greatly enhanced during growth on different pectin related polysaccharides. An extracellular β-galactosidase was purified 26-fold by ammonium sulfate precipitation, gel filtration and ion exchange
Christine Riou, Georges Freyssinet, Michel Fèvre   +2 more
openaire   +1 more source

Role of glycosylation in secretion and stability of micromycetes α-galactosidase [PDF]

The Ukrainian Biochemical Journal, 2014
The effect of the glycosylation inhibitors (tunicamycin and 2-deoxy-D-glucose) on the activity, stabili­ty and production of fungal glycosidases has been studied.
N. V. Borzova, O. V. Gudzenko, L. D. Varbanets   +2 more
doaj   +1 more source