Results 11 to 20 of about 902,322 (261)

Centaurin-α₂ interacts with β-tubulin and stabilizes microtubules. [PDF]

PLoS ONE, 2012
Centaurin-α₂ is a GTPase-activating protein for ARF (ARFGAP) showing a diffuse cytoplasmic localization capable to translocate to membrane, where it binds phosphatidylinositols. Taking into account that Centaurin-α₂ can localize in cytoplasm and that its
Paola Zuccotti, Daniele Cartelli, Michela Stroppi, Vittorio Pandini, Marco Venturin, Alessandro Aliverti, Elena Battaglioli, Graziella Cappelletti, Paola Riva   +8 more
doaj   +3 more sources

Linking acetylated α-Tubulin redistribution to α-Synuclein pathology in brain of Parkinson’s disease patients [PDF]

npj Parkinson's Disease
Highly specialized microtubules in neurons are crucial to both health and disease of the nervous system, and their properties are strictly regulated by different post-translational modifications, including α-Tubulin acetylation.
Samanta Mazzetti, Federica Giampietro, Alessandra Maria Calogero, Huseyin Berkcan Isilgan, Gloria Gagliardi, Chiara Rolando, Francesca Cantele, Miriam Ascagni, Manuela Bramerio, Giorgio Giaccone, Ioannis Ugo Isaias, Gianni Pezzoli, Graziella Cappelletti   +12 more
doaj   +2 more sources

Matrix stiffness‐induced α‐tubulin acetylation is required for skin fibrosis formation through activation of Yes‐associated protein [PDF]

MedComm, 2023
Skin fibrosis, a pathological process featured by fibroblast activation and extracellular matrix (ECM) deposition, makes a significant contribution to morbidity.
Dongsheng Wen, Ya Gao, Yangdan Liu, Chiakang Ho, Jiaming Sun, Lu Huang, Yuxin Liu, Qingfeng Li, Yifan Zhang   +8 more
doaj   +2 more sources

Ethanol Administration in Mice Leads to Sex-Specific Changes in the Acetylation of α-Tubulin in the Cerebellum [PDF]

Brain Sciences
Background: Acetylation of α-tubulin is an important post-translational modification that helps maintain microtubules’ stability and dynamics, including axonal transport, cell signaling, and overall neuronal integrity.
Abosede Elesinnla, Rehana Khatoon, Nicholas Kleinert, Junfang Wu, Jaylyn Waddell, Tibor Kristian   +5 more
doaj   +2 more sources

MFN2 coordinates mitochondria motility with α-tubulin acetylation and this regulation is disrupted in CMT2A [PDF]

iScience
Summary: Mitofusin-2 (MFN2), a large GTPase residing in the mitochondrial outer membrane and mutated in Charcot-Marie-Tooth type 2 disease (CMT2A), is a regulator of mitochondrial fusion and tethering with the ER.
Atul Kumar, Delfina Larrea, Maria Elena Pero, Paola Infante, Marilisa Conenna, Grace J. Shin, Vincent Van Elias, Wesley B. Grueber, Lucia Di Marcotullio, Estela Area-Gomez, Francesca Bartolini   +10 more
doaj   +2 more sources

Acetylated α-Tubulin and α-Synuclein: Physiological Interplay and Contribution to α-Synuclein Oligomerization. [PDF]

Int J Mol Sci, 2023
Emerging evidence supports that altered α-tubulin acetylation occurs in Parkinson's disease (PD), a neurodegenerative disorder characterized by the deposition of α-synuclein fibrillary aggregates within Lewy bodies and nigrostriatal neuron degeneration ...
Calogero AM, Basellini MJ, Isilgan HB, Longhena F, Bellucci A, Mazzetti S, Rolando C, Pezzoli G, Cappelletti G.   +8 more
europepmc   +4 more sources

Modulating microtubule stability via α-tubulin acetylation partially restores Golgi fragmentation in spinal muscular atrophy. [PDF]

Turk J Biol
Background/aim: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by the loss of survival of motor neuron (SMN) protein. SMN deficiency leads to perturbations of the cytoskeleton, including microtubules, which are mainly involved in ...
Zobaroğlu Özer P, Gözüböyük M, Çetin Ö, Hensel N, Emecen G, Malik A, Bowerman M, Claus P, Erdem Yurter H, Bora Akoğlu G.   +9 more
europepmc   +2 more sources

Corrigendum to: “Genetic polymorphism at the β-tubulin locus among human and animal isolates ofCryptosporidium parvum” [PDF]

FEMS Microbiology Letters, 1999
The authors would like to make the following correction: In Fig. 1 on page 176, a base (an Adenine) is …
Simone Cacciò, Wieger Homan, Karin Dijk, Edoardo Pozio   +3 more
openaire   +1 more source

The dual functions of α-tubulin acetylation in cellular apoptosis and autophage induced by tanespimycin in lung cancer cells

Cancer Cell International, 2020
Background Reversible acetylation of α-tubulin has been implicated in modulating microtuble structures and functions, which may subsequently involve in cellular apoptosis and autophage.
Qilin Wang, Xiangguo Liu
doaj   +1 more source

Sequence diversity of β-tubulin (tubA) gene inPhaeosphaeria nodorumandP. avenaria [PDF]

FEMS Microbiology Letters, 2005
Full-length coding sequences of the beta-tubulin gene (tubA) were PCR-amplified and sequenced from 42 Phaeosphaeria isolates, including 16 P. nodorum and 23 P. avenaria species from cereals, two Polish isolates from rye (Secale cereale L.), and one isolate from dallis grass (Paspalum dilatatum Poir).
Arkadiusz, Malkus, Ewelina, Reszka, Chung-Jan, Chang, Edward, Arseniuk, Pi-Fang Linda, Chang, Peter P, Ueng   +5 more
openaire   +2 more sources