Results 31 to 40 of about 902,322 (261)
Resistance to benzimidazole at a population of gastrointestinal nematode, especially Haemonchus contortus is a widespread problem. Therefore, anthelmintic will not effective anymore. Benzimidazole resistance in nematode has been shown to be heritable and defined as an increase in frequency of individual worms able to drug tolerate.
Dyah Haryuningtyas +2 more
openaire +1 more source
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. [PDF]
BACKGROUND: Antimalarial interventions designed to impact on the transmissible sexual stages of Plasmodium falciparum are evaluated by measurement of peripheral gametocyte carriage in vivo and infectivity to mosquitoes.
Sutherland, Colin J +10 more
core +1 more source
Platelet inhibition is the main treatment strategy to prevent atherothrombotic complications after acute coronary syndrome or percutaneous coronary intervention.
Valentine Robaux +9 more
doaj +1 more source
Regulation of Tubulin Gene Expression: From Isotype Identity to Functional Specialization
Genomes of higher eukaryotes encode a large tubulin gene superfamily consisting of at least six α and six β-tubulin isotypes. While some α and β-tubulin isotypes are ubiquitously expressed, others are cell-type specific.
Ivana Gasic
doaj +1 more source
Cryo-EM structure of VASH1-SVBP bound to microtubules
The dynamic tyrosination-detyrosination cycle of α-tubulin regulates microtubule functions. Perturbation of this cycle impairs mitosis, neural physiology, and cardiomyocyte contraction.
Faxiang Li +7 more
doaj +1 more source
An essential role for α4A-tubulin in platelet biogenesis
Alpha4A-tubulin is the predominant α-tubulin isotype in platelets. Mutations in α4A-tubulin cause abnormal platelet biogenesis and marginal band formation in mice and in a patient, establishing an essential role of this tubulin isotype.
Catherine Strassel +22 more
doaj +1 more source
A Comprehensive Study on the Electrostatic Properties of Tubulin-Tubulin Complexes in Microtubules
Microtubules are key players in several stages of the cell cycle and are also involved in the transportation of cellular organelles. Microtubules are polymerized by α/β tubulin dimers with a highly dynamic feature, especially at the plus ends of the ...
Wenhan Guo +4 more
doaj +1 more source
Reduced tubulin tyrosination as an early marker of mercury toxicity in differentiating N2a cells [PDF]
The aims of this work were to compare the effects of methyl mercury chloride and Thimerosal on neurite/process outgrowth and microtubule proteins in differentiating mouse N2a neuroblastoma and rat C6 glioma cells.
Lawton, M +4 more
core +1 more source
TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. [PDF]
TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown.
Andreas Schwingshackl +3 more
doaj +1 more source
Correlation of serum anti-tubulin-α-1c antibody level and disease activity index in BD patients.
(a) anti-tubulin-α-1c antibody level positively correlated with ESR; (b) anti-tubulin-α-1c antibody level positively correlated with CRP; (c) anti-tubulin-α-1c antibody level positively correlated with BVAS. BVAS, Birmingham vasculitis activity score.
Cibo Huang (444680) +9 more
core +1 more source

