Results 31 to 40 of about 902,322 (261)

Sequence variability of the β Tubulin isotype-1 genes in benzimidazole resistant strains of Haemonchus contortus, a nematode parasite of sheep

open access: yesJurnal Ilmu Ternak dan Veteriner, 2012
Resistance to benzimidazole at a population of gastrointestinal nematode, especially Haemonchus contortus is a widespread problem. Therefore, anthelmintic will not effective anymore. Benzimidazole resistance in nematode has been shown to be heritable and defined as an increase in frequency of individual worms able to drug tolerate.
Dyah Haryuningtyas   +2 more
openaire   +1 more source

Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. [PDF]

open access: yes, 2010
BACKGROUND: Antimalarial interventions designed to impact on the transmissible sexual stages of Plasmodium falciparum are evaluated by measurement of peripheral gametocyte carriage in vivo and infectivity to mosquitoes.
Sutherland, Colin J   +10 more
core   +1 more source

Dual antiplatelet therapy is associated with high α-tubulin acetylation in circulating platelets from coronary artery disease patients

open access: yesPlatelets, 2023
Platelet inhibition is the main treatment strategy to prevent atherothrombotic complications after acute coronary syndrome or percutaneous coronary intervention.
Valentine Robaux   +9 more
doaj   +1 more source

Regulation of Tubulin Gene Expression: From Isotype Identity to Functional Specialization

open access: yesFrontiers in Cell and Developmental Biology, 2022
Genomes of higher eukaryotes encode a large tubulin gene superfamily consisting of at least six α and six β-tubulin isotypes. While some α and β-tubulin isotypes are ubiquitously expressed, others are cell-type specific.
Ivana Gasic
doaj   +1 more source

Cryo-EM structure of VASH1-SVBP bound to microtubules

open access: yeseLife, 2020
The dynamic tyrosination-detyrosination cycle of α-tubulin regulates microtubule functions. Perturbation of this cycle impairs mitosis, neural physiology, and cardiomyocyte contraction.
Faxiang Li   +7 more
doaj   +1 more source

An essential role for α4A-tubulin in platelet biogenesis

open access: yesLife Science Alliance, 2019
Alpha4A-tubulin is the predominant α-tubulin isotype in platelets. Mutations in α4A-tubulin cause abnormal platelet biogenesis and marginal band formation in mice and in a patient, establishing an essential role of this tubulin isotype.
Catherine Strassel   +22 more
doaj   +1 more source

A Comprehensive Study on the Electrostatic Properties of Tubulin-Tubulin Complexes in Microtubules

open access: yesCells, 2023
Microtubules are key players in several stages of the cell cycle and are also involved in the transportation of cellular organelles. Microtubules are polymerized by α/β tubulin dimers with a highly dynamic feature, especially at the plus ends of the ...
Wenhan Guo   +4 more
doaj   +1 more source

Reduced tubulin tyrosination as an early marker of mercury toxicity in differentiating N2a cells [PDF]

open access: yes, 2007
The aims of this work were to compare the effects of methyl mercury chloride and Thimerosal on neurite/process outgrowth and microtubule proteins in differentiating mouse N2a neuroblastoma and rat C6 glioma cells.
Lawton, M   +4 more
core   +1 more source

TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements. [PDF]

open access: yesPLoS ONE, 2015
TREK-1 deficient alveolar epithelial cells (AECs) secrete less IL-6, more MCP-1, and contain less F-actin. Whether these alterations in cytokine secretion and F-actin content are related remains unknown.
Andreas Schwingshackl   +3 more
doaj   +1 more source

Correlation of serum anti-tubulin-α-1c antibody level and disease activity index in BD patients.

open access: yes, 2018
(a) anti-tubulin-α-1c antibody level positively correlated with ESR; (b) anti-tubulin-α-1c antibody level positively correlated with CRP; (c) anti-tubulin-α-1c antibody level positively correlated with BVAS. BVAS, Birmingham vasculitis activity score.
Cibo Huang (444680)   +9 more
core   +1 more source

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