Results 61 to 70 of about 902,322 (261)

Structural intermediates in the assembly of taxoid-induced microtubules and GDP-tubulin double rings: time-resolved X-ray scattering

, 1996
We have studied the self-association reactions of purified GDP-liganded tubulin into double rings and taxoid-induced microtubules, employing synchrotron time-resolved x-ray solution scattering.
Diaz, J.F., Bordas, J., Andreu, J.M., Towns-Andrews, Elizabeth, Diakun, G.P., Diakun, G., Towns-Andrews, E.   +6 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

MOESM3 of A novel resveratrol derivative induces mitotic arrest, centrosome fragmentation and cancer cell death by inhibiting γ-tubulin

, 2019
Additional file 3: Figure S3. Localization of different spindle pole proteins in 3,4,4′-TMS treated cells. HCT116 cells were exposed to 40 μM 3,4,4′-TMS and then immunostained with anti-Aurora A and anti-α-tubulin antibodies, anti-TPX2 and anti-α-tubulin
Zulema Percario (6574118), Francesca Degrassi (231524), Daniela Trisciuoglio (132747), Renata Cozzi (651264), Gianandrea Traversi (6574112), David Staid (6574115), Veronica Morea (1495819), Mario Fiore (231517), Roberto Antonioletti (201575)   +8 more
core   +1 more source

Novel α-Tubulin Mutations Conferring Resistance to Dinitroaniline Herbicides in Lolium rigidum

Frontiers in Plant Science, 2018
The dinitroaniline herbicides (particularly trifluralin) have been globally used in many crops for selective grass weed control. Consequently, trifluralin resistance has been documented in several important crop weed species and has recently reached a ...
Zhizhan Chu, Zhizhan Chu, Jinyi Chen, Alex Nyporko, Heping Han, Qin Yu, Stephen Powles   +6 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

MOESM5 of A novel resveratrol derivative induces mitotic arrest, centrosome fragmentation and cancer cell death by inhibiting γ-tubulin

, 2019
Additional file 5: Figure S5. Comparison of colchicine binding to γ/γ- and α/β-tubulin dimer. β- and γ-tubulin are shown as ribbon and coloured dark green and cyan, respectively.
Zulema Percario (6574118), Francesca Degrassi (231524), Daniela Trisciuoglio (132747), Renata Cozzi (651264), Gianandrea Traversi (6574112), David Staid (6574115), Veronica Morea (1495819), Mario Fiore (231517), Roberto Antonioletti (201575)   +8 more
core   +1 more source

Impact of the non-acetylatable α-tubulin expression.

, 2022
HeLa cells were co-transfected with plasmids encoding BHRF1-HA (or EV) and mCherry-α-tubulin K40A (or WT). (A) Immunoblot analysis of acetyl-α-tubulin, α-tubulin and HA. (B) Confocal images of EVtransfected cells immunostained for TOM20.
Audrey Esclatine (8067290), Eva Hernandez (9282440), Damien Glon (9282428), Frédérique Quignon (9282446), Clarisse Berlioz-Torrent (77466), Géraldine Vilmen (9282425), Christian Poüs (9282452), Guillaume Beauclair (7245176), Marion Lussignol (9282434), Vincent Maréchal (357460), Daniel Perdiz (9282443)   +10 more
core   +1 more source

Cryo-EM structures of the tubulin cofactors reveal the molecular basis of alpha/beta-tubulin biogenesis

Nature Communications
Microtubule polarity and dynamic polymerization arise from the self-association properties of the αβ-tubulin heterodimer. For decades, it has remained unclear how the tubulin cofactors TBCD, TBCE, TBCC, and the Arl2 GTPase mediate the biogenesis of αβ ...
Aryan Taheri, Zhoaqian Wang, Bharti Singal, Fei Guo, Jawdat Al-Bassam   +4 more
doaj   +1 more source

Conservation of dinitroani-line/phosphorothioamidate site of α-tubulin in Plasmodium species distributed in India

Фактори експериментальної еволюції організмів, 2019
Aim. To evaluate polymorphism of dinitroaniline/phosphorothioamidate binding site in α-tubulin molecules from Plasmodium species (P. falciparum, P. vivax, P. ovale, and P. malariae) and strains discovered in India. Methods.
P. A. Karpov, O. M. Demchuk, S. P. Ozheredov, S. I. Spivak, A. I. Yemets, Ya. B. Blume   +5 more
doaj   +1 more source

Differential modification of the C-terminal tails of different α-tubulins and their importance for microtubule function in vivo

eLife, 2023
Microtubules (MTs) are built from α-/β-tubulin dimers and used as tracks by kinesin and dynein motors to transport a variety of cargos, such as mRNAs, proteins, and organelles, within the cell.
Mengjing Bao, Ruth E Dörig, Paula Maria Vazquez-Pianzola, Dirk Beuchle, Beat Suter   +4 more
doaj   +1 more source