Results 141 to 150 of about 101,136 (248)

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Species-selective activation of a β-galactosidase fluorogenic probe. [PDF]

Sci Rep
Jaskot K, Mielcarek A, Popenda Ł, Kertmen A, Grześkowiak BF, Barciszewski J, Perrigue PM.   +6 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Dataset on the analysis of β-galactosidase immobilization efficiency on aminomethyl polystyrene (AMP) resin in syringe and column reactors. [PDF]

Data Brief
Boehme T, Straub B, Eschenhagen U, Schmidt MS.   +3 more
europepmc   +1 more source

Lily Transcription Factors LlPLATZ1 and LlMYB4 Orchestrate the Homeostasis of Heat Stress Responses via Antagonistic Regulation of LlHSF24

Plant Biotechnology Journal, EarlyView.
ABSTRACT Heat stress significantly damages crop yield and quality. PLATZ (PLANT A/T‐RICH SEQUENCE‐AND ZINC‐BINDING PROTEIN) transcription factors play pivotal roles in plant growth, development, and environmental stress responses. While the functions of PLATZ members in response to drought and salt stress are well characterised, their roles in heat ...
Xue Gong, Jun Xiang, Ziwei Liao, Tian Zhang, Liping Ding, Qianqian Fang, Nianjun Teng, Ze Wu   +7 more
wiley   +1 more source

Frosted DNA: β-Galactosidase Control of Oligonucleotide Activity. [PDF]

Chemistry
Sinsel F, Külp M, Rieger MA, Heckel A.
europepmc   +1 more source

A Highly Conserved SNARE‐Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking

Plant Biotechnology Journal, EarlyView.
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk, Peitong Li, Hafiz Muhammad Khalid Abbas, Mst Shamira Sultana, Sarbottam Piya, Nicole Coffey, Cengizhan Öztürk, Sobhan Bahrami Zadegan, Susan Thomas Laird, Mazen Alazem, Samantha P. Nuzzi, J. Hollis Rice, Chris Wyman, Tessa Burch‐Smith, Vince Pantalone, Tarek Hewezi   +15 more
wiley   +1 more source

β-galactosidase-targeted senolytic prodrug ameliorates preclinical models of post-traumatic osteoarthritis. [PDF]

EBioMedicine
Li Q, Wu T, Fan Y, Cheng J, Wang J, Xu B, Sun M, Gong X, Deng H, Ao Y, Hu X.   +10 more
europepmc   +1 more source

A Specific Sinorhizobium Flagellin Suppresses Legume Nodulation Through Immune Activation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Bacterial flagellin‐activated immunity plays a crucial role in shaping plant‐microbe interactions, leading to either parasitism, mutualism, or commensalism. In the legume‐rhizobium symbiosis, while it has been hypothesized that rhizobial infection involves avoidance of plant immunity following flagellin perception, direct evidence supporting ...
Li Liu, Yaohua Li, Shuangcheng Ye, Chuanzheng Wei, Ziang Yan, Huanhui Yang, Hui Zhu, Gary Stacey, Yangrong Cao   +8 more
wiley   +1 more source

Galactooligosaccharide Production Using Immobilized <i>Aspergillus oryzae</i> β-Galactosidase, Part I: Characterization and Influence of Reaction Conditions. [PDF]

Int J Mol Sci
Antošová M, Adamíková JK, Polakovič M.   +2 more
europepmc   +1 more source