Results 161 to 170 of about 2,747,637 (331)

Oxygen Sensitivity of Reporter Genes: Implications for Preclinical Imaging of Tumor Hypoxia

Molecular Imaging, 2007
Reporter gene techniques have been applied toward studying the physiologic phenomena associated with tumor hypoxia, a negative prognostic indicator.
Ivana Cecic, Denise A. Chan, Patrick D. Sutphin, Pritha Ray, Sanjiv Sam Gambhir, Amato J. Giaccia, Edward E. Graves   +6 more
doaj   +1 more source

Blood‐Based Biomarkers in Alzheimer's Disease: Advances in Detection Technologies and Clinical Applications

AGING MEDICINE, EarlyView.
Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley   +1 more source

Differential Diagnosis of Mucopolysaccharidoses Types I, II, III, IVA, and VI Through Analysis of Leukocytic Inclusions

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mucopolysaccharidoses (MPS) are lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs), which can lead to cytoplasmic alterations in leukocytes. The objective of this study was to characterize leukocyte inclusions in patients with different types of MPS and assess their diagnostic relevance.
Márcio A. W. Melo, Marcelo S. Kertenetzky, Cristina M. Silveira, Maíra M. Ribeiro, Paula F. Medeiros, Gabriela S. Arcanjo   +5 more
wiley   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Subcellular Localization of β-Galactosidase Protein from Probiotic Limosilactobacillus fermentum LF08 Strain: Probability of Cell Wall Association

Applied Sciences
Lactic acid bacteria exhibit high adaptability to their environment due to their wide variety of enzymes. Despite extensive knowledge of bacterial cell walls, the subcellular localization of β-galactosidase in many probiotic lactic acid bacteria ...
Kristijan Hristovski, Ramez Jamal Mitri Al Massadeh, Botond Kálmán Süli, Stefan Savo Micevic, Sofia Radja Ziane, György Brezovcsik, Zsuzsanna Kiss, Géza Hitka, Anh M. T. Tran, Erika Bujna, Quang D. Nguyen   +10 more
doaj   +1 more source

G M1 -gangliosidosis: Chromosome 3 assignment of the β -galactosidase-A gene ( β GAL A )

, 1979
The structural gene (βGAL A ) coding for lysosomal β-galactosidase- A (EC 3.2.1.23) has been assigned to human chromosome 3 using man-mouse somatic cell hybrids.
Scrafford-Wolff, Linda R., Shows, Thomas B., Brown, Judith A., Meisler, Miriam H.   +3 more
core   +1 more source

Kinetics of β-galactosidase Production by Lactobacillus bulgaricus During pH Controlled Batch Fermentation in Three Commercial Bulk Starter Media

Applied Food Biotechnology, 2015
The potential of bulk starter fermentation strategy for production of a cost-effective and GRAS source of β-galactosidase from a starter culture strain Lactobacillus bulgaricus was investigated.
Saeed Abbasalizadeh, Mohammad Amin Hejazi, Mahdi Pesaran Hajiabbas   +2 more
doaj  

The sRNA vvrr1 Modulates the VarS/VarA‐Csr System via LeuO to Regulate Biofilm Formation and Virulence in Vibrio alginolyticus

Animal Research and One Health, EarlyView.
vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul, Lei Wen, Lingmin Zhao, Bei Huang, Jiang Zheng, Binfu Xu, Lixing Huang   +6 more
wiley   +1 more source

UTILITY OF FUNCTIONALIZED AGAROSE NANOPARTICLES IN HYDROLYZING LACTOSE IN BATCH REACTORS FOR DAIRY INDUSTRIES

Química Nova
The present study investigates the synthesis of agarose nanoparticles (ANPs) and its surface modification by galactose for the immobilization of β-galactosidase. Galactose modified ANPs retained 91% enzyme activity upon immobilization.
Shakeel Ahmed Ansari, Syed Ismail Ahmad, Mohammad Alam Jafri, Muhammad Imran Naseer, Rukhsana Satar   +4 more
doaj   +1 more source

Differential partitioning of β-galactosidase and β-glucosidase using aqueous two phase extraction

, 2011
Aqueous two phase extraction (ATPE) is used for the first time for simultaneous separation and purification of β-galactosidase and β-glucosidase from barley (Hordeum vulgare).
K.S.M.S. Raghavarao, Raghavarao, K. S. M. S., Hemavathi, A. B., A.B. Hemavathi   +3 more
core   +1 more source