Results 171 to 180 of about 102,730 (251)

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

Characterization of a β-Galactosidase from <i>Kosakonia oryzendophytica</i> and Its Heterologous Expression in <i>Bacillus subtilis</i> for Galactooligosaccharides Production. [PDF]

Molecules
Cheng Z, Jin X, Zhang Y, Ni D, Zhu Y, Xu W, Zhang W, Mu W.   +7 more
europepmc   +1 more source

A Single‐Nucleotide Substitution Generates a de Novo Promoter That Activates a Latent Metabolic Bypass in Escherichia coli

Molecular Microbiology, EarlyView.
A chromosomal mutation allows bypass of deletion of the Escherichia coli fabH gene. The bypass results from creation of a new promoter that drives increased madA transcription, resulting in increased synthesis of acetyl‐acyl carrier protein by decarboxylation of malonyl‐acyl carrier protein.
Qiaoqiao Guo, Qi Zou, Jilong Qin, Makrina Totsika, Yaoqin Hong, John E. Cronan   +5 more
wiley   +1 more source

Immobilized β-galactosidase BgaC from Bifidobacterium adolescentis retains stability and activity during repeated cycles of use. [PDF]

Appl Microbiol Biotechnol
Mulualem DM, Dwan O, Kilcoyne M, O'Byrne C, Boyd A.   +4 more
europepmc   +1 more source

A Nutrient‐Responsive LuxR Regulator Orchestrates Effector Gene Expression Across the Legionella Genus

Molecular Microbiology, EarlyView.
LexR1 is a LuxR‐type regulator that links nutrient sensing to effector gene expression in Legionella. Activated by a casamino acid‐derived ligand, LexR1 directly controls multiple effector genes using a conserved regulatory element present in numerous putative effectors across different Legionella species.
Chen Adler, Gil Segal
wiley   +1 more source

MRI detection of senescent cells in porcine knee joints with a β-galactosidase responsive Gd-chelate. [PDF]

Npj Imaging
Nernekli K, Mangarova DB, Suryadevara V, Hajipour M, Tang JH, Wang J, Liang T, Harris M, Ueyama T, Lyons JK, Moseley ME, Roudi R, Pisani L, von Krüchten R, Duwa R, Lu-Liang SY, Shokri Varniab Z, Vasyliv I, Das N, Murayama M, Shinohara I, Pratx G, Goodman SB, Meade TJ, Daldrup-Link HE.   +24 more
europepmc   +1 more source

The Role of torS and torT Transcription in Driving a Bet‐Hedging Strategy for Trimethylamine N‐Oxide Reductase Expression in Escherichia coli

Molecular Microbiology, EarlyView.
Low basal activity of divergent promoters driving transcription of the trimethylamine N‐oxide (TMAO) sensor TorT and kinase TorS is integral to an O2‐regulated bet‐hedging strategy for continued E. coli growth upon the onset of anaerobiosis. This, along with repression by IscR, promotes noise in the TorS to TorT ratio, which is critical for adaptation ...
Erin L. Mettert, Jeffrey N. Carey, Wilma Ross, Mark Goulian, Patricia J. Kiley   +4 more
wiley   +1 more source

Correlation Between the Proportion of Senescence-Associated β-Galactosidase-Stained CD8+ T Cells and Age: A Cross-Sectional Study in Japan. [PDF]

Int J Mol Sci
Tsubokawa M, Shimizu Y, Yazaki M, Shimodan S, Noguchi M, Yamazaki A, Watanabe T, Ocho M, Sakurada T, Hirose Y, Saito J, Ishii Y.   +11 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Encapsulation of β-Galactosidase into Polyallylamine/Polystyrene Sulphonate Polyelectrolyte Microcapsules. [PDF]

Int J Mol Sci
Chebykin YS, Musin EV, Kim AL, Tikhonenko SA.   +3 more
europepmc   +1 more source