Results 181 to 190 of about 101,136 (248)

Interactions of Mucus Monosaccharides and the Epidermal Microbiome in Four Benthic Elasmobranchs

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Here we collected mucus and microbes from the skin of Elasmobranchs to identify interactions between mucus and the microbial community. We identified key microbial genes involved in the metabolism of mucus carbohydrates in Elasmobranchs. ABSTRACT Epidermal mucus is a complicated mixture of macromolecules which acts as the first line of defence for ...
Emma N. Kerr, Long Yu, Ryan D. Hesse, Chloe N. Roberts, Vincent Bulone, Lauren Meyer, Robert A. Edwards, Michael P. Doane, Elizabeth A. Dinsdale   +8 more
wiley   +1 more source

Corrigendum: Infection of a β-galactosidase-deficient mouse strain with Theiler's murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease. [PDF]

Front Immunol
Wannemacher R, Stegmann F, Eikelberg D, Bühler M, Li D, Kohale SK, Asawapattanakul T, Ebbecke T, Raulf MK, Baumgärtner W, Lepenies B, Gerhauser I.   +11 more
europepmc   +1 more source

FGF21‐Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3

Aging Cell, Volume 25, Issue 4, April 2026.
FGF21 upregulates SIRT1 to promote the deacetylation of FOXO3 at sites K241, K258, K289, and K568, thereby activating PINK1/Parkin‐dependent mitophagy, suppressing nucleus pulposus cell senescence, and delaying intervertebral disc degeneration. ABSTRACT Intervertebral Disc Degeneration (IDD) is a common degenerative spinal disease and a leading cause ...
Zuo‐long Wu, Rui Ran, Qi‐qi Xie, Cong Zhang, Ya‐jun Chen, Peng Cheng, Ke‐Ping Wang, Hai‐hong Zhang   +7 more
wiley   +1 more source

Enhancing β-Galactosidase Performance for Galactooligosaccharides Preparation via Strategic Glucose Re-Tunneling. [PDF]

Int J Mol Sci
Zhao J, Niu D, Liu J, Jin Z, Mchunu NP, Singh S, Wang Z.   +6 more
europepmc   +1 more source

Senescence‐Driven IL‐17A Inflammatory Circuit Promotes Epithelial–Mesenchymal Transition (EMT) and Progression in Age‐Related Posterior Subcapsular Cataracts

Aging Cell, Volume 25, Issue 4, April 2026.
Using multi‐region human PSC samples, we identified EMT as a consistent pathological feature. Mechanistically, senescent LECs secrete IL‐17A, a representative SASP factor, which activates NF‐κB signaling. NF‐κB further amplifies SASP production, thereby establishing a senescence–inflammation feedback loop that drives EMT, sustains pathological ...
Yan Ni, Yu Ma, Zewen Ren, Yi Zhu, Liangping Liu, Runping Duan, Lu Qin, Yang Chen, Rong Ju, Yingyan Qin, Mingxing Wu   +10 more
wiley   +1 more source

Safety evaluation of the food enzyme β-galactosidase from the non-genetically modified <i>Kluyveromyces lactis</i> strain LAC-01. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Sramkova M, Van Loveren H, Vernis L, Lunardi S, Andryszkiewicz M, Marini E, Liu Y.   +17 more
europepmc   +1 more source

Differential Gene Expression in Human Hippocampus With Aging

Aging Cell, Volume 25, Issue 4, April 2026.
2 complementary analysis from a transcriptome study in human hippocampal samples of different ages revealed a set of genes differentially expressed in aged individuals linked to inflammation and immune system pathways, DNA repair (RAD23) or neural activity.
Ander Saenz‐Antoñanzas, Manuel Moreno‐Valladares, Maider Muñoz‐Culla, Sara Cruces‐Salguero, Jon Landa, Ainhoa Alberro, Jhonatan Vergara‐Arce, Marta Arroyo‐Izaga, David Otaegui, Ander Matheu   +9 more
wiley   +1 more source

Isolation and characterization of a β-galactosidase from Lactobacillus helveticus for industrial processing. [PDF]

JDS Commun
Ruiz-Ramírez S, Jiménez-Flores R.
europepmc   +1 more source

MicroRNA‐128‐3p Deficiency Alleviates Bone Loss in Age‐Related Osteoporosis via Activation of Canonical Wnt Signaling

Aging Cell, Volume 25, Issue 4, April 2026.
Working model: MiR‐128‐3p inhibited the canonical Wnt signaling pathway by targeting Dvl2, resulting in reduced OB differentiation and age‐related osteoporosis. ABSTRACT MicroRNA‐128‐3p (miR‐128‐3p) has emerged as a crucial regulator of the aging process and age‐associated disorders. Recent research highlights the vital role of miR‐128‐3p in osteoclast
Gengyang Shen, Kun Chen, Qi Shang, Honglin Chen, Yu Liu, Guifeng Chen, Weicheng Qin, Jiahui He, Yuzhuo Zhang, Wenhua Zhao, Weiyu Qiu, Jingzhi Zhang, Hui Ren, Xiaobing Jiang   +13 more
wiley   +1 more source

Lysis of Escherichia coli by colicin Ib contributes to bacterial cross-feeding by releasing active β-galactosidase. [PDF]

ISME J
Lerminiaux NA, Kaufman JM, Schnell LJ, Workman SD, Suchan DM, Kröger C, Ingalls BP, Cameron ADS.   +7 more
europepmc   +1 more source